PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
6257884-2	1981	Beta-1 and beta-2 adrenergic receptor blockade were produced with atenolol and butoxamine, respectively.	Atenolol	66-74	adrenoceptor beta 2	Homo sapiens	11-37	
12154173-3	2002	When ISO plus the beta(1)-AR antagonist atenolol (ISO-beta(2)-AR stimulation) or 1 microM zinterol (ZIN-beta(2)-AR stimulation) increased I(Ca,L), ACh-induced inhibition of I(Ca,L) was significantly smaller, at -21 +/- 3 and -24 +/- 3 %, respectively.	Atenolol	40-48	adrenoceptor beta 2	Homo sapiens	54-64	
7504142-4	1993	There was no significant difference in total or subtype beta-adrenoceptor densities, but basal and isoproterenol stimulated adenylate cyclase activity were significantly greater in the atenolol-treated group, as was the intrinsic activity of the beta 2-adrenoceptor partial agonist procaterol, suggesting that chronic therapy with xamoterol does not downregulate human cardiac beta-adrenoceptors in vivo.	Atenolol	185-193	adrenoceptor beta 2	Homo sapiens	246-265	
3037216-2	1987	The beta 1-selective antagonists atenolol and LK 203-030 inhibited specific [125I]-(-)-cyanopindolol binding according to a one binding site model with low affinity in nearly all subjects, pointing to a homogeneous beta 2-adrenoceptor population.	Atenolol	33-41	adrenoceptor beta 2	Homo sapiens	215-234	
2866785-3	1985	Atenolol produced significantly less reduction of essential and isoprenaline-induced tremor than the non-selective drugs, confirming the importance of beta 2-adrenoceptor blockade in these effects.	Atenolol	0-8	adrenoceptor beta 2	Homo sapiens	151-170	
17003101-7	2007	Furthermore, atenolol and ICI 118,551, a beta1- and beta2-adrenoceptor antagonist, respectively, reversed the stimulatory action of nicotine on the expression of PKC, ERK1/2 phosphorylation, and COX-2 together with cell proliferation.	Atenolol	13-21	adrenoceptor beta 2	Homo sapiens	52-70	
15687340-6	2005	The beta2-AR was stimulated with two doses of salbutamol (50 and 100 ng/kg fat-free mass per minute) after blockade of the beta1-adrenergic receptors with atenolol.	Atenolol	155-163	adrenoceptor beta 2	Homo sapiens	4-12	
1971535-4	1990	There was an enhanced responsiveness to (-)epinephrine (atenolol treated: -log M EC50, 7.57 +/- 0.07; non-beta-blocker treated: -log M EC50, 6.77 +/- 0.17; p less than 0.001), and the relative importance of beta 2-adrenoceptor stimulation was increased for both (-)norepinephrine and (-)epinephrine.	Atenolol	56-64	adrenoceptor beta 2	Homo sapiens	207-226	
2713221-0	1989	Effects of atenolol vs diltiazem on the haemodynamic effects of an inhaled beta 2-adrenoceptor agonist.	Atenolol	11-19	adrenoceptor beta 2	Homo sapiens	75-94	
2575521-6	1989	These results show that beta 2-adrenoceptor blockade by atenolol is a dose-dependent phenomenon, which may be measured by the attenuation of salbutamol-induced hypokalaemia.	Atenolol	56-64	adrenoceptor beta 2	Homo sapiens	24-43	
2575521-7	1989	However, beta 2-adrenoceptor blockade by atenolol 200 mg was less than that by propranolol 40 mg.	Atenolol	41-49	adrenoceptor beta 2	Homo sapiens	9-28	
25026350-1	2014	CONTEXT: Propranolol, atenolol, and ICI118,551 are non-selective beta-adrenergic receptor (AR), beta1-AR, and beta2-AR antagonists, respectively.	Atenolol	22-30	adrenoceptor beta 2	Homo sapiens	110-118	
21963428-6	2012	In contrast, pretreatment of cells with a third beta(2)AR antagonist, atenolol resulted in an increase in OTR-mediated ERK1/2 activation.	Atenolol	70-78	adrenoceptor beta 2	Homo sapiens	48-57