PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16934679-0	2006	Cyclooxygenase-2-dependent neuronal death proceeds via superoxide anion generation.	Superoxides	55-71	prostaglandin-endoperoxide synthase 2	Mus musculus	0-16	
16934679-6	2006	Cortical neurons with enhanced COX-2 expression showed superoxide generation, GSH depletion, and lipid peroxidation in response to low doses of Fe2+, and all of these changes were repressed by MnTBAP or NS398.	Superoxides	55-65	prostaglandin-endoperoxide synthase 2	Mus musculus	31-36	
16934679-7	2006	Consistent with this pharmacological data, cortical neurons prepared from COX-2 knockout mice showed marked reductions in LPS-induced Fe2+ -toxicity enhancement and superoxide generation.	Superoxides	165-175	prostaglandin-endoperoxide synthase 2	Mus musculus	74-79	
16934679-8	2006	These results suggest that COX-2 functions as a cellular factor which induces superoxide-mediated cell death in primary cortical neurons.	Superoxides	78-88	prostaglandin-endoperoxide synthase 2	Mus musculus	27-32	
10718345-6	2000	Resveratrol treatment caused a significant impairment of cyclooxygenase-2 (COX-2) induction stimulated by LPS and PMA or by O2- or H2O2 exposure.	Superoxides	124-126	prostaglandin-endoperoxide synthase 2	Mus musculus	57-73	
10718345-6	2000	Resveratrol treatment caused a significant impairment of cyclooxygenase-2 (COX-2) induction stimulated by LPS and PMA or by O2- or H2O2 exposure.	Superoxides	124-126	prostaglandin-endoperoxide synthase 2	Mus musculus	75-80	
25714890-0	2015	The superoxide anion donor, potassium superoxide, induces pain and inflammation in mice through production of reactive oxygen species and cyclooxygenase-2.	Superoxides	4-20	prostaglandin-endoperoxide synthase 2	Mus musculus	138-154	
21833043-5	2011	RESULTS: At resting state, the superoxide production in aortic and cardiac tissues was lower in cyclo-oxygenase-2 deficient than in the wild type or in cyclo-oxygenase-1 deficient mice.	Superoxides	31-41	prostaglandin-endoperoxide synthase 2	Mus musculus	96-113	
21833043-9	2011	CONCLUSIONS: Cyclo-oxygenase-2 pathway plays a major role in the superoxide generation as well as in the angiotensin II-induced oxidative stress and blood pressure.	Superoxides	65-75	prostaglandin-endoperoxide synthase 2	Mus musculus	13-30