PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16287844-5 2005 Our results suggest that the MEC1 pathway in sod1Delta mutant strains is sensitive to the altered cellular redox state due to increased superoxide anions and establish a new relationship between SOD1, LYS7, and the MEC1-mediated checkpoint response to replication arrest and DNA damage in S. cerevisiae. Superoxides 136-153 protein kinase MEC1 Saccharomyces cerevisiae S288C 29-33