PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11899098-5 2002 Reactive oxygen species (e.g., superoxide, peroxynitrite, hydrogen peroxide and hydroxyl radical) are all potential reactants capable of initiating DNA single strand breakage, with subsequent activation of the nuclear enzyme poly (ADP ribose) synthetase (PARS), leading to eventual severe energy depletion of the cells, and necrotic-type cell death. Superoxides 31-41 glutamyl-prolyl-tRNA synthetase 1 Homo sapiens 255-259 11525764-10 2001 Reactive oxygen species (e.g., superoxide, peroxynitrite, hydroxyl radical and hydrogen peroxide) are all potential reactants capable of initiating DNA single-strand breakage, with subsequent activation of the nuclear enzyme poly (ADP-ribose) synthetase (PARS), leading to eventual severe energy depletion of the cells, and necrotic-type cell death. Superoxides 31-41 glutamyl-prolyl-tRNA synthetase 1 Homo sapiens 255-259