PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20831906-1 2010 The production of cGMP by the soluble form of guanylate cyclase (sGC) in bovine pulmonary arteries (BPA) is controlled by cytosolic NADPH maintaining reduced thiol and heme sites on sGC needed for activation by NO, and the levels of Nox oxidase-derived superoxide and peroxide that influence pathways regulating sGC activity. Superoxides 253-263 guanylate cyclase Bos taurus 46-63 2881544-2 1987 This mechanism of guanylate cyclase activation is not blocked by scavengers for superoxide anion or hydroxyl radical, but is selectively inhibited by methylene blue, inactivation of catalase and ethanol. Superoxides 80-96 guanylate cyclase Bos taurus 18-35