PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22952763-0	2012	Expression of human paraoxonase 1 decreases superoxide levels and alters bacterial colonization in the gut of Drosophila melanogaster.	Superoxides	44-54	paraoxonase 1	Homo sapiens	20-33	
25038992-5	2014	Recent studies demonstrated that the intracellular PON proteins; PON2 and PON3 (i) are associated with mitochondria and mitochondria-associated membranes, (ii) modulate mitochondria-dependent superoxide production, and (iii) prevent apoptosis.	Superoxides	192-202	paraoxonase 1	Homo sapiens	51-54	
22952763-7	2012	We found that PON1 alters expression of multiple oxidative stress genes and decreases superoxide anion levels in normal and germ-free D. melanogaster.	Superoxides	86-102	paraoxonase 1	Homo sapiens	14-18	
22952763-9	2012	PON1 expression directly decreased superoxide anion levels and altered bacterial colonization of the gut and its gene expression profile, highlighting the complex nature of the interaction between host genotype and gut microbiota.	Superoxides	35-51	paraoxonase 1	Homo sapiens	0-4	
15865106-3	2005	Polymorphic variations in NAD(P)H oxidase p22phox and paraoxonase 1 (PON1) enzyme activities may alter superoxide production or the rate of chemical metabolism, respectively, and this may influence the risk for CRC.	Superoxides	103-113	paraoxonase 1	Homo sapiens	54-67	
15865106-3	2005	Polymorphic variations in NAD(P)H oxidase p22phox and paraoxonase 1 (PON1) enzyme activities may alter superoxide production or the rate of chemical metabolism, respectively, and this may influence the risk for CRC.	Superoxides	103-113	paraoxonase 1	Homo sapiens	69-73	
12633754-11	2003	Upon incubation of PON1(0)/E(0) derived macrophages with human PON1 (7.5 arylesterase units/ml), cellular peroxides content was decreased by 18%, macrophage superoxide anion release was decreased by 33%, and macrophage-mediated oxidation of LDL was reduced by 22%.	Superoxides	157-173	paraoxonase 1	Homo sapiens	19-23	
12633754-11	2003	Upon incubation of PON1(0)/E(0) derived macrophages with human PON1 (7.5 arylesterase units/ml), cellular peroxides content was decreased by 18%, macrophage superoxide anion release was decreased by 33%, and macrophage-mediated oxidation of LDL was reduced by 22%.	Superoxides	157-173	paraoxonase 1	Homo sapiens	63-67