PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16380122-0 2006 Hirsutenone inhibits phorbol ester-induced upregulation of COX-2 and MMP-9 in cultured human mammary epithelial cells: NF-kappaB as a potential molecular target. hirsutenone 0-11 matrix metallopeptidase 9 Homo sapiens 69-74 16380122-7 2006 The upregulation of MMP-9 by TPA was also significantly reduced by hirsutenone. hirsutenone 67-78 matrix metallopeptidase 9 Homo sapiens 20-25 16380122-12 2006 In summary, hirsutenone inhibits the TPA-induced upregulation of COX-2 and MMP-9 in human breast epithelial cells, possibly by targeting NF-kappaB, which may contribute to its chemopreventive effects. hirsutenone 12-23 matrix metallopeptidase 9 Homo sapiens 75-80