PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16045972-5 2005 To test this hypothesis, we evaluated the effects of chronic donepezil, nicotine and haloperidol on expression levels of 5-HT2A mRNA and 5-HT2A receptor density in select brain regions. Nicotine 72-80 5-hydroxytryptamine (serotonin) receptor 2A Mus musculus 121-127 16045972-12 2005 The cortex was the only area where donepezil, nicotine and haloperidol significantly reduced the 5-HT2A receptor density. Nicotine 46-54 5-hydroxytryptamine (serotonin) receptor 2A Mus musculus 97-112 16045972-13 2005 The results suggest that the anti-tic properties of donepezil, nicotine and haloperidol in this paradigm might be due to antagonism of cortical 5-HT2A receptors. Nicotine 63-71 5-hydroxytryptamine (serotonin) receptor 2A Mus musculus 144-150