PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15723229-1 2005 RATIONALE: Following repeated injections with nicotine paired with a distinctive environment, some studies have reported that the distinctive context becomes a conditioned stimulus (CS) capable of eliciting conditioned corticosterone (CORT) release. Nicotine 46-54 cortistatin Rattus norvegicus 235-239 21396990-1 2011 Hypothalamic-pituitary-adrenal (HPA) responses to single-dose nicotine (NIC) are sexually diergic: Female rats have higher adrenocorticotropic hormone (ACTH) and corticosterone (CORT) responses than do males. Nicotine 62-70 cortistatin Rattus norvegicus 178-182 20171986-7 2010 Both basal and nicotine-induced (0.5mg/kg sc) elevations in urinary CORT were consistent between groups of animals with weights ranging from 200 to 400 g. The magnitude of urinary CORT elevation induced by nicotine (0.5mg/kg sc) was found to be similar to that induced by a forced swim stressor in male Lister ) antagonist mecamylamine (0.05-0.5mg/kg sc) dose-dependently reversed the effects of nicotine (0.5mg/kg sc) on urinary CORT. Nicotine 15-23 cortistatin Rattus norvegicus 68-72 20171986-7 2010 Both basal and nicotine-induced (0.5mg/kg sc) elevations in urinary CORT were consistent between groups of animals with weights ranging from 200 to 400 g. The magnitude of urinary CORT elevation induced by nicotine (0.5mg/kg sc) was found to be similar to that induced by a forced swim stressor in male Lister ) antagonist mecamylamine (0.05-0.5mg/kg sc) dose-dependently reversed the effects of nicotine (0.5mg/kg sc) on urinary CORT. Nicotine 15-23 cortistatin Rattus norvegicus 180-184 20171986-7 2010 Both basal and nicotine-induced (0.5mg/kg sc) elevations in urinary CORT were consistent between groups of animals with weights ranging from 200 to 400 g. The magnitude of urinary CORT elevation induced by nicotine (0.5mg/kg sc) was found to be similar to that induced by a forced swim stressor in male Lister ) antagonist mecamylamine (0.05-0.5mg/kg sc) dose-dependently reversed the effects of nicotine (0.5mg/kg sc) on urinary CORT. Nicotine 15-23 cortistatin Rattus norvegicus 180-184 20171986-7 2010 Both basal and nicotine-induced (0.5mg/kg sc) elevations in urinary CORT were consistent between groups of animals with weights ranging from 200 to 400 g. The magnitude of urinary CORT elevation induced by nicotine (0.5mg/kg sc) was found to be similar to that induced by a forced swim stressor in male Lister ) antagonist mecamylamine (0.05-0.5mg/kg sc) dose-dependently reversed the effects of nicotine (0.5mg/kg sc) on urinary CORT. Nicotine 206-214 cortistatin Rattus norvegicus 68-72 20171986-7 2010 Both basal and nicotine-induced (0.5mg/kg sc) elevations in urinary CORT were consistent between groups of animals with weights ranging from 200 to 400 g. The magnitude of urinary CORT elevation induced by nicotine (0.5mg/kg sc) was found to be similar to that induced by a forced swim stressor in male Lister ) antagonist mecamylamine (0.05-0.5mg/kg sc) dose-dependently reversed the effects of nicotine (0.5mg/kg sc) on urinary CORT. Nicotine 206-214 cortistatin Rattus norvegicus 180-184 20171986-7 2010 Both basal and nicotine-induced (0.5mg/kg sc) elevations in urinary CORT were consistent between groups of animals with weights ranging from 200 to 400 g. The magnitude of urinary CORT elevation induced by nicotine (0.5mg/kg sc) was found to be similar to that induced by a forced swim stressor in male Lister ) antagonist mecamylamine (0.05-0.5mg/kg sc) dose-dependently reversed the effects of nicotine (0.5mg/kg sc) on urinary CORT. Nicotine 206-214 cortistatin Rattus norvegicus 180-184 20171986-7 2010 Both basal and nicotine-induced (0.5mg/kg sc) elevations in urinary CORT were consistent between groups of animals with weights ranging from 200 to 400 g. The magnitude of urinary CORT elevation induced by nicotine (0.5mg/kg sc) was found to be similar to that induced by a forced swim stressor in male Lister ) antagonist mecamylamine (0.05-0.5mg/kg sc) dose-dependently reversed the effects of nicotine (0.5mg/kg sc) on urinary CORT. Nicotine 206-214 cortistatin Rattus norvegicus 68-72 20171986-7 2010 Both basal and nicotine-induced (0.5mg/kg sc) elevations in urinary CORT were consistent between groups of animals with weights ranging from 200 to 400 g. The magnitude of urinary CORT elevation induced by nicotine (0.5mg/kg sc) was found to be similar to that induced by a forced swim stressor in male Lister ) antagonist mecamylamine (0.05-0.5mg/kg sc) dose-dependently reversed the effects of nicotine (0.5mg/kg sc) on urinary CORT. Nicotine 206-214 cortistatin Rattus norvegicus 180-184 20171986-7 2010 Both basal and nicotine-induced (0.5mg/kg sc) elevations in urinary CORT were consistent between groups of animals with weights ranging from 200 to 400 g. The magnitude of urinary CORT elevation induced by nicotine (0.5mg/kg sc) was found to be similar to that induced by a forced swim stressor in male Lister ) antagonist mecamylamine (0.05-0.5mg/kg sc) dose-dependently reversed the effects of nicotine (0.5mg/kg sc) on urinary CORT. Nicotine 206-214 cortistatin Rattus norvegicus 180-184 19766150-3 2010 In this study, we investigated in rats whether CST inhibits vascular calcification induced by vitamin D3 and nicotine treatment in vivo and calcification of cultured rat vascular smooth muscular cells (VSMCs) induced by beta-glycerophosphate in vitro and the underlying mechanism. Nicotine 109-117 cortistatin Rattus norvegicus 47-50 20117222-2 2010 We previously reported sexually diergic, dose-dependent HPA responses in vivo following nicotine administration: Male rats had greater arginine vasopressin (AVP) responses than females, and female rats had greater adrenocorticotropic hormone (ACTH) and corticosterone (CORT) responses than males. Nicotine 88-96 cortistatin Rattus norvegicus 269-273 16311047-8 2006 In vitro CRH, ACTH, and CORT responses to nicotine were significantly increased at 10 min and returned to baseline by 30 min, the CRH and ACTH responses from female tissues being greater than responses from male tissues. Nicotine 42-50 cortistatin Rattus norvegicus 24-28 15723229-2 2005 Conversely, other studies have found that exposure to the CS results in conditioned attenuation of nicotine-induced CORT release. Nicotine 99-107 cortistatin Rattus norvegicus 116-120 15723229-6 2005 RESULTS: CORT levels were higher after nicotine than after saline, and higher in the paired than in the unpaired condition. Nicotine 39-47 cortistatin Rattus norvegicus 9-13 15723229-8 2005 CONCLUSIONS: The results supported the notion that a CS associated with nicotine effects elicit a conditioned response (CR) in the form of CORT release. Nicotine 72-80 cortistatin Rattus norvegicus 139-143 15723229-9 2005 Future research will be needed to examine whether conditioned CORT release can explain the context-dependent attenuations of nicotine-induced CORT. Nicotine 125-133 cortistatin Rattus norvegicus 62-66 15723229-9 2005 Future research will be needed to examine whether conditioned CORT release can explain the context-dependent attenuations of nicotine-induced CORT. Nicotine 125-133 cortistatin Rattus norvegicus 142-146 15820527-6 2005 Nicotine increased CORT and ACTH levels of Sprague-Dawley females only. Nicotine 0-8 cortistatin Rattus norvegicus 19-23 7870994-5 1993 A significant reduction in withdrawal latencies was obtained for CORT pretreated rats compared to animals given only nicotine. Nicotine 117-125 cortistatin Rattus norvegicus 65-69 7870994-8 1993 Results also suggest that a conditioned release of endogenous CORT was triggered by stimuli associated with nicotine delivery. Nicotine 108-116 cortistatin Rattus norvegicus 62-66 7870994-9 1993 These data are consistent with the hypothesis that a conditioned release of CORT could contribute to the development of tolerance to some of nicotine"s effects. Nicotine 141-149 cortistatin Rattus norvegicus 76-80 24997359-6 2014 Prenatal nicotine exposure caused noticeably lower body weights, higher IUGR rates of fetal rats, and elevated maternal and fetal corticosterone (CORT) levels compared to the controls. Nicotine 9-17 cortistatin Rattus norvegicus 146-150