PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18778441-0 2008 Chronic effect of nicotine on serotonin transporter mRNA in the raphe nucleus of rats: reversal by co-administration of bupropion. Nicotine 18-26 solute carrier family 6 member 4 Rattus norvegicus 30-51 18778441-8 2008 RESULTS: Chronic nicotine infusion resulted in the reduction of 5HTT mRNA expression, which lasted through withdrawal day 2. Nicotine 17-25 solute carrier family 6 member 4 Rattus norvegicus 64-68 18778441-10 2008 CONCLUSIONS: Chronic nicotine infusion reduces the synthesis of 5HTT protein, which may consequently precipitate depression during nicotine withdrawal, but co-administration of bupropion may ameliorate withdrawal symptoms by counteracting nicotine"s effect on 5HTT. Nicotine 21-29 solute carrier family 6 member 4 Rattus norvegicus 64-68 18778441-10 2008 CONCLUSIONS: Chronic nicotine infusion reduces the synthesis of 5HTT protein, which may consequently precipitate depression during nicotine withdrawal, but co-administration of bupropion may ameliorate withdrawal symptoms by counteracting nicotine"s effect on 5HTT. Nicotine 131-139 solute carrier family 6 member 4 Rattus norvegicus 64-68 18778441-10 2008 CONCLUSIONS: Chronic nicotine infusion reduces the synthesis of 5HTT protein, which may consequently precipitate depression during nicotine withdrawal, but co-administration of bupropion may ameliorate withdrawal symptoms by counteracting nicotine"s effect on 5HTT. Nicotine 131-139 solute carrier family 6 member 4 Rattus norvegicus 64-68 14515338-1 2003 We sought to investigate the effect of nicotine exposure (chronic and acute) on serotonin transporter (SERT) activity in two regions of the brain important for behavioral effects of nicotine. Nicotine 39-47 solute carrier family 6 member 4 Rattus norvegicus 80-101 14515338-1 2003 We sought to investigate the effect of nicotine exposure (chronic and acute) on serotonin transporter (SERT) activity in two regions of the brain important for behavioral effects of nicotine. Nicotine 39-47 solute carrier family 6 member 4 Rattus norvegicus 103-107 14515338-1 2003 We sought to investigate the effect of nicotine exposure (chronic and acute) on serotonin transporter (SERT) activity in two regions of the brain important for behavioral effects of nicotine. Nicotine 182-190 solute carrier family 6 member 4 Rattus norvegicus 80-101 14515338-1 2003 We sought to investigate the effect of nicotine exposure (chronic and acute) on serotonin transporter (SERT) activity in two regions of the brain important for behavioral effects of nicotine. Nicotine 182-190 solute carrier family 6 member 4 Rattus norvegicus 103-107 14515338-6 2003 SERT binding studies, using prefrontocortical or hippocampal membrane preparations, revealed that chronic nicotine exposure significantly increased B(max) which correlated to an increase in SERT density. Nicotine 106-114 solute carrier family 6 member 4 Rattus norvegicus 0-4 14515338-6 2003 SERT binding studies, using prefrontocortical or hippocampal membrane preparations, revealed that chronic nicotine exposure significantly increased B(max) which correlated to an increase in SERT density. Nicotine 106-114 solute carrier family 6 member 4 Rattus norvegicus 190-194 11164385-0 2001 Nicotine exposure during pregnancy is a factor which influences serotonin transporter density in the rat brain. Nicotine 0-8 solute carrier family 6 member 4 Rattus norvegicus 64-85 11164385-1 2001 We examined the effects of nicotine exposure during pregnancy on serotonin transporter (SERT) expression in the brain. Nicotine 27-35 solute carrier family 6 member 4 Rattus norvegicus 65-86 11164385-1 2001 We examined the effects of nicotine exposure during pregnancy on serotonin transporter (SERT) expression in the brain. Nicotine 27-35 solute carrier family 6 member 4 Rattus norvegicus 88-92 11164385-3 2001 Irrespective of the route of administration, nicotine increased SERT density in the forebrain on postnatal day 22, but not in the other brain regions. Nicotine 45-53 solute carrier family 6 member 4 Rattus norvegicus 64-68 16463401-4 2006 Our data suggest that activation of nAChRs, quite likely via PKA, increase the activity of the SERT in the PFC and, thereby, can alter 5-HT levels in a region important in the behavioral effects of nicotine and 5-HT. Nicotine 198-206 solute carrier family 6 member 4 Rattus norvegicus 95-99 15464092-4 2004 Nicotine treatment increased dopamine transporter densities and decreased serotonin transporter densities in periadolescent rats. Nicotine 0-8 solute carrier family 6 member 4 Rattus norvegicus 74-95