PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20384816-3	2010	In this study we used an animal model of nicotine addiction to examine the possibility that changes in insular cortex levels of dopamine (DA)- and cAMP-regulated phosphoprotein of 32 kDa (DARPP-32), a phosphoprotein enriched in DA neurons containing DA D1 receptors, may be associated with changes in vulnerability to nicotine addiction.	Nicotine	41-49	protein phosphatase 1, regulatory (inhibitor) subunit 1B	Rattus norvegicus	188-196	
20384816-3	2010	In this study we used an animal model of nicotine addiction to examine the possibility that changes in insular cortex levels of dopamine (DA)- and cAMP-regulated phosphoprotein of 32 kDa (DARPP-32), a phosphoprotein enriched in DA neurons containing DA D1 receptors, may be associated with changes in vulnerability to nicotine addiction.	Nicotine	318-326	protein phosphatase 1, regulatory (inhibitor) subunit 1B	Rattus norvegicus	188-196	
17687035-3	2007	Systemic cyclosporine administration decreased calcineurin activity in the brain, attenuated nicotine-mediated locomotor sensitization, and blocked the effects of nicotine on DARPP32 (dopamine- and cAMP-regulated phosphoprotein-32) activation in the striatum.	Nicotine	163-171	protein phosphatase 1, regulatory (inhibitor) subunit 1B	Rattus norvegicus	175-182	
17687035-3	2007	Systemic cyclosporine administration decreased calcineurin activity in the brain, attenuated nicotine-mediated locomotor sensitization, and blocked the effects of nicotine on DARPP32 (dopamine- and cAMP-regulated phosphoprotein-32) activation in the striatum.	Nicotine	163-171	protein phosphatase 1, regulatory (inhibitor) subunit 1B	Rattus norvegicus	184-230	
35581520-9	2022	The increased rate of DARPP-32 phosphorylation in adult PSH rats might result from excessive glutamatergic stimulation of the dopaminergic (DA) neurons of the ventral tegmental area (VTA) caused by activation of presynaptic nAChR by nicotine.	Nicotine	233-241	protein phosphatase 1, regulatory (inhibitor) subunit 1B	Rattus norvegicus	22-30	
22952905-0	2012	Environmental enrichment alters nicotine-mediated locomotor sensitization and phosphorylation of DARPP-32 and CREB in rat prefrontal cortex.	Nicotine	32-40	protein phosphatase 1, regulatory (inhibitor) subunit 1B	Rattus norvegicus	97-105