PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16959216-5 2006 Similarly, the medium levels of both ADMA and lactate dehydrogenase were markedly elevated in umbilical vein endothelial cells (HUVECs) treated with nicotine (10 microM) for 48 h. Nicotine-induced endothelial damages were markedly attenuated by L-arginine or overexpression of DDAH-II. Nicotine 149-157 dimethylarginine dimethylaminohydrolase 2 Rattus norvegicus 277-284 16959216-5 2006 Similarly, the medium levels of both ADMA and lactate dehydrogenase were markedly elevated in umbilical vein endothelial cells (HUVECs) treated with nicotine (10 microM) for 48 h. Nicotine-induced endothelial damages were markedly attenuated by L-arginine or overexpression of DDAH-II. Nicotine 180-188 dimethylarginine dimethylaminohydrolase 2 Rattus norvegicus 277-284 16959216-6 2006 Nicotine greatly downregulated both mRNA and protein levels of DDAH-II, and decreased DDAH activity in HUVECs. Nicotine 0-8 dimethylarginine dimethylaminohydrolase 2 Rattus norvegicus 63-70