PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27460145-4 2016 Incubation with Ws-Lynx1 decreases nicotine-mediated extracellular signal-regulated kinase phosphorylation in PC12 cells and striatal neurons, indicating that binding of Ws-Lynx1 is sufficient to inhibit signaling downstream of nAChRs. Nicotine 35-43 Ly6/neurotoxin 1 Rattus norvegicus 19-24 27460145-4 2016 Incubation with Ws-Lynx1 decreases nicotine-mediated extracellular signal-regulated kinase phosphorylation in PC12 cells and striatal neurons, indicating that binding of Ws-Lynx1 is sufficient to inhibit signaling downstream of nAChRs. Nicotine 35-43 Ly6/neurotoxin 1 Rattus norvegicus 173-178 27460145-5 2016 The effect of nicotine in PC12 cells is independent of alpha7 or alpha4beta2 nAChRs, suggesting that Lynx1 can affect the function of native non-alpha7, non-alpha4beta2 nAChR subtypes. Nicotine 14-22 Ly6/neurotoxin 1 Rattus norvegicus 101-106