PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23586521-13	2013	Surprisingly, when RIC-3 was coexpressed with alpha4beta2 receptors nicotine-induced upregulation was prevented.	Nicotine	68-76	RIC3 acetylcholine receptor chaperone	Homo sapiens	19-24	
27430244-9	2016	However, in the cells co-expressing human RIC-3 and alpha7 nicotinic acetylcholine receptor, nicotine induced calcium influx via the alpha7 nicotinic acetylcholine receptor in a concentration-dependent manner (concentration required to elicit 50% of the maximal effect=29.21 microM).	Nicotine	93-101	RIC3 acetylcholine receptor chaperone	Homo sapiens	42-47	
23586521-8	2013	Could the coexpression of RIC-3 modulate the extent of nicotine-induced upregulation not only for alpha7 receptors but also alpha4beta2 receptors?	Nicotine	55-63	RIC3 acetylcholine receptor chaperone	Homo sapiens	26-31	
23586521-16	2013	These results also show that nicotine-mediated upregulation of alpha4beta2 receptors can be dynamically regulated by the presence of the chaperone, RIC-3.	Nicotine	29-37	RIC3 acetylcholine receptor chaperone	Homo sapiens	148-153