PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16149045-0	2005	Nicotinic and PDGF-receptor function are essential for nicotine-stimulated mitogenesis in human vascular smooth muscle cells.	Nicotine	55-63	platelet derived growth factor receptor beta	Homo sapiens	14-27	
16149045-3	2005	Nicotine"s effect on human aortic vascular smooth muscle cells (HaVSMC) and the role of the nicotinic receptor (nAChR), platelet-derived growth factor (PDGF), and the PDGF-receptor (PDGF-R) in this response were studied.	Nicotine	0-8	platelet derived growth factor receptor beta	Homo sapiens	182-188	
16149045-10	2005	PDGF-R blockade with the PDGF-R antagonist tyrphostin AG 1295 decreased nicotine-induced DNA synthesis and cell division (0.25 +/- 0.01, 0.44 +/- 0.2-fold decrease, respectively).	Nicotine	72-80	platelet derived growth factor receptor beta	Homo sapiens	0-6	
16149045-10	2005	PDGF-R blockade with the PDGF-R antagonist tyrphostin AG 1295 decreased nicotine-induced DNA synthesis and cell division (0.25 +/- 0.01, 0.44 +/- 0.2-fold decrease, respectively).	Nicotine	72-80	platelet derived growth factor receptor beta	Homo sapiens	25-31	
16149045-11	2005	PDGF-R blockade reversed nicotine-stimulated increases in PDGF release, PDGF-BB transcripts, and PDGF-receptor levels (0.68 +/- 0.34; 0.46 +/- 0.01; 0.28 +/- 0.01-fold decrease, respectively).	Nicotine	25-33	platelet derived growth factor receptor beta	Homo sapiens	0-6	
16149045-11	2005	PDGF-R blockade reversed nicotine-stimulated increases in PDGF release, PDGF-BB transcripts, and PDGF-receptor levels (0.68 +/- 0.34; 0.46 +/- 0.01; 0.28 +/- 0.01-fold decrease, respectively).	Nicotine	25-33	platelet derived growth factor receptor beta	Homo sapiens	97-110	
16149045-13	2005	PDGF-BB/PDGF-R interaction is vital in nicotine"s mitogenic actions on human aortic smooth muscle cells.	Nicotine	39-47	platelet derived growth factor receptor beta	Homo sapiens	8-14