PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33146402-0 2021 Nicotine exhausts CD8+ T cells against tumor cells through increasing miR-629-5p to repress IL2RB-mediated granzyme B expression. Nicotine 0-8 granzyme B Homo sapiens 107-117 33146402-12 2021 We further validated that nicotine reduced granzyme B levels using a nuclear imaging technique, and demonstrated that nicotine exhausted peripheral blood mononuclear cells against HCC827 growth in the humanized tumor xenografts. Nicotine 26-34 granzyme B Homo sapiens 43-53