PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10932071-7	2000	Nicotine, at a concentration comparable with that found in the highest-tar cigarettes (200 microg/mL), suppressed the production of IL-2, IFN-gamma, and TNF-alpha by only 21% to 38%.	Nicotine	0-8	interferon gamma	Homo sapiens	138-147	
22537161-6	2012	IFN-gamma and RA could collaborate with nicotine in elevating the expression of MUC4, utilizing E2F1 and STAT1 transcription factors.	Nicotine	40-48	interferon gamma	Homo sapiens	0-9	
16966384-4	2006	In the present study, we found that nicotine inhibited the IL-18-enhanced expression of ICAM-1, B7.2, and CD40 on monocytes, and the production of IL-12, IFN-gamma, and TNF-alpha by PBMC.	Nicotine	36-44	interferon gamma	Homo sapiens	154-163	
29803914-8	2018	When combined, TLR3 + 8 and TLR4 + 8 synergistically optimized nicDC maturation and IFN-gamma secretion from nicotine-exposed NK (nicNK) during co-cultures.	Nicotine	109-117	interferon gamma	Homo sapiens	84-93	
24137042-7	2014	In relation to the objectives of the study, we concluded that (a) IFN-gamma at biologically relevant concentrations significantly enhanced pro-inflammatory responses; (b) CSE, nicotine and cotinine dysregulated the inflammatory response and that the effects of CSE were different from those of the individual components, nicotine and cotinine; (c) when both IFN-gamma and CSE were present, IFN-gamma masked the effect of CSE.	Nicotine	321-329	interferon gamma	Homo sapiens	66-75	
17254563-5	2007	The IC50 values of nicotine for inhibition of the IL-18-enhanced ICAM-1 expression, IFN-gamma production and proliferation were 1, 1 and 2 microM, respectively.	Nicotine	19-27	interferon gamma	Homo sapiens	84-93