PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35017179-5	2022	High-affinity nAChRs can incorporate additional subunits, including beta3, alpha6, or alpha5 subunits, with the resulting nAChR subtypes playing discrete and dissociable roles in the stimulatory actions of nicotine on brain dopamine transmission.	Nicotine	206-214	uncharacterized protein LOC107802668	Nicotiana tabacum	68-92	
35017179-7	2022	nAChRs containing alpha3 and beta4 subunits are responsible for the low-affinity nicotine binding sites in the brain and are enriched in brain sites involved in aversion, including the medial habenula, interpeduncular nucleus, and nucleus of the solitary tract, brain sites in which alpha5 nAChR subunits are also expressed.	Nicotine	81-89	uncharacterized protein LOC107802668	Nicotiana tabacum	18-34	
33380469-2	2021	alpha3* nAChRs are densely expressed by medial habenula (mHb) neurons, which project almost exclusively to the interpeduncular nucleus (IPn) and are known to regulate nicotine avoidance behaviors.	Nicotine	167-175	uncharacterized protein LOC107802668	Nicotiana tabacum	0-7	
22647317-4	2012	Chromosomal aberrations (and in particular all strains showing A1-3 reciprocal translocation) are especially frequent in strains collected on tobacco plants, and we suggest that a clastogenic effect of nicotine, further benefited by the holocentric nature of aphid chromosomes, could be at the basis of the observed phenomenon.	Nicotine	202-210	uncharacterized protein LOC107802668	Nicotiana tabacum	63-67