PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32250310-0	2020	Nicotine Promotes AbetaPP Nonamyloidogenic Processing via RACK1-Dependent Activation of PKC in SH-SY5Y-AbetaPP695 Cells.	Nicotine	0-8	receptor for activated C kinase 1	Homo sapiens	58-63	
32250310-9	2020	We also found that nicotine elevated the expression of phosphorylated PKC (P-PKC) and RACK1 on the cytomembrane.	Nicotine	19-27	receptor for activated C kinase 1	Homo sapiens	86-91	
32250310-11	2020	Genetic knockdown RACK1 significantly inhibited P-PKC, and consequently abolished the increase of ADAM10 and C83 by nicotine.	Nicotine	116-124	receptor for activated C kinase 1	Homo sapiens	18-23	
32250310-12	2020	CONCLUSION: Taken together, these results indicate that nicotine effectively promotes AbetaPP nonamyloidogenic processing via RACK1-dependent activation of PKC in SH-SY5Y-AbetaPP695 cells and could be a potential molecule for AD treatment.	Nicotine	56-64	receptor for activated C kinase 1	Homo sapiens	126-131