PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3370533-5 1988 The results demonstrated that during simultaneous release of both hormones, vasopressin is released in greater proportion following restraint stress, hemorrhage, isotonic hypovolemia, and nicotine, whereas oxytocin is released in greater proportion following endotoxin or hypertonic saline. Nicotine 188-196 arginine vasopressin Rattus norvegicus 76-87 19210408-4 1989 The microinjection of nicotine (0.1, 1 or 10 HQ) into the paraventricular nucleus had only questionable effects on vasopressin release and mean arterial blood pressure; heart rate was unaffected. Nicotine 22-30 arginine vasopressin Rattus norvegicus 115-126 2914084-8 1989 In addition, nicotine was found to stimulate the release of VP from SON, but not PVN, cultures in both SHR and WKY explants. Nicotine 13-21 arginine vasopressin Rattus norvegicus 60-62 2907166-14 1988 2 shows an excitatory relay through a cholinoceptive area on the ventral surface of the brain stem which has been termed the "nicotine-sensitive area" because topical application of nicotine to this area in the cat released vasopressin without oxytocin. Nicotine 126-134 arginine vasopressin Rattus norvegicus 224-235 2907166-14 1988 2 shows an excitatory relay through a cholinoceptive area on the ventral surface of the brain stem which has been termed the "nicotine-sensitive area" because topical application of nicotine to this area in the cat released vasopressin without oxytocin. Nicotine 182-190 arginine vasopressin Rattus norvegicus 224-235 2908045-7 1988 The effect of nicotine on AVP production was confirmed in vitro using the rat hypothalamo-neurohypophysial system preparation where nicotine increased AVP secretion in a dose-dependent manner. Nicotine 14-22 arginine vasopressin Rattus norvegicus 26-29 2908045-7 1988 The effect of nicotine on AVP production was confirmed in vitro using the rat hypothalamo-neurohypophysial system preparation where nicotine increased AVP secretion in a dose-dependent manner. Nicotine 14-22 arginine vasopressin Rattus norvegicus 151-154 2908045-7 1988 The effect of nicotine on AVP production was confirmed in vitro using the rat hypothalamo-neurohypophysial system preparation where nicotine increased AVP secretion in a dose-dependent manner. Nicotine 132-140 arginine vasopressin Rattus norvegicus 26-29 2908045-7 1988 The effect of nicotine on AVP production was confirmed in vitro using the rat hypothalamo-neurohypophysial system preparation where nicotine increased AVP secretion in a dose-dependent manner. Nicotine 132-140 arginine vasopressin Rattus norvegicus 151-154 3681699-0 1987 Nicotine-induced release of vasopressin in the conscious rat: role of opioid peptides and hemodynamic effects. Nicotine 0-8 arginine vasopressin Rattus norvegicus 28-39 3681699-1 1987 Nicotine has been shown to stimulate the release of vasopressin and to cause significant hemodynamic changes. Nicotine 0-8 arginine vasopressin Rattus norvegicus 52-63 3681699-2 1987 The mechanisms leading to enhanced vasopressin secretion and the vascular consequences of the high plasma vasopressin levels during nicotine infusion have not yet been determined. Nicotine 132-140 arginine vasopressin Rattus norvegicus 106-117 3681699-3 1987 Therefore, the purposes of the present study were 1) to examine in normal conscious rats the role of opioid peptides in the nicotine-induced increase in plasma vasopressin levels and 2) to assess the role of vasopressin in the hemodynamic effects of nicotine (20 micrograms/min for 15 min) using a specific V1 antagonist of the vascular actions of vasopressin. Nicotine 124-132 arginine vasopressin Rattus norvegicus 160-171 3681699-4 1987 Plasma vasopressin levels were significantly increased in the nicotine-treated animals (39.5 +/- 10 vs. 3.7 +/- 0.6 pg/ml in the controls, P less than .01). Nicotine 62-70 arginine vasopressin Rattus norvegicus 7-18 6686153-2 1983 Nicotine caused a significant release of both vasopressin and oxytocin from the neural lobe. Nicotine 0-8 arginine vasopressin Rattus norvegicus 46-57 3681699-8 1987 Thus, these results suggest that the nicotine-induced secretion of vasopressin is not mediated by opioid receptors and that the high plasma vasopressin levels do not exert any significant hemodynamic effect on cardiac output or blood flow distribution. Nicotine 37-45 arginine vasopressin Rattus norvegicus 67-78 2874742-3 1986 Hexamethonium did, however, block the increase in blood pressure, the decrease in heart rate, and the very small elevation in the plasma vasopressin concentration induced by nicotine (10 micrograms icv). Nicotine 174-182 arginine vasopressin Rattus norvegicus 137-148 3796791-0 1986 Naloxone effects on plasma vasopressin and oxytocin concentrations elevated by histamine, nicotine, isoproterenol and an acute increase in [NaCl] in cerebrospinal fluid. Nicotine 90-98 arginine vasopressin Rattus norvegicus 27-38 3796791-10 1986 The concentrations of oxytocin and vasopressin in plasma were elevated (p less than 0.05) by histamine, isoproterenol (30 and 120 micrograms/kg), increases[NaCl] in CSF, and nicotine at the higher (1.5 mg/kg) but not lower (0.15 mg/kg) dose. Nicotine 174-182 arginine vasopressin Rattus norvegicus 35-46 7449837-1 1980 Water deprivation, drinking water containing 2% NaCl, or systemic injection with histamine or nicotine markedly increased plasma levels of vasopressin in rats. Nicotine 94-102 arginine vasopressin Rattus norvegicus 139-150 6312746-0 1983 Intravenous injections of nicotine induce very rapid and discrete reductions of hypothalamic catecholamine levels associated with increases of ACTH, vasopressin and prolactin secretion. Nicotine 26-34 arginine vasopressin Rattus norvegicus 149-160 7310708-6 1981 Prior superfusion with xylocaine or intravenous infusions of 800 micrograms atropine-methyl bromate abolished this response, although vasopressin was still released to nicotine in atropine-blocked rats. Nicotine 168-176 arginine vasopressin Rattus norvegicus 134-145 615118-0 1977 Effect of contraction per se on the nicotine-induced outflow of 3H-norepinephrine from rat isolated vas deferens. Nicotine 36-44 arginine vasopressin Rattus norvegicus 100-103 436724-1 1979 Acetylcholine and nicotine stimulated vasopressin (VP) release from the organ-cultured rat hypothalamo-neurohypophyseal system (HNS). Nicotine 18-26 arginine vasopressin Rattus norvegicus 38-49 436724-1 1979 Acetylcholine and nicotine stimulated vasopressin (VP) release from the organ-cultured rat hypothalamo-neurohypophyseal system (HNS). Nicotine 18-26 arginine vasopressin Rattus norvegicus 51-53 436724-2 1979 Nicotinic antagonists, hexamethonium, tetraethylammonium chloride, and trimethaphan blocked VP release in response to acetylcholine and nicotine. Nicotine 136-144 arginine vasopressin Rattus norvegicus 92-94 677957-1 1978 Nicotine and DMPP caused contraction of rat isolated vas deferens. Nicotine 0-8 arginine vasopressin Rattus norvegicus 53-56 597785-1 1977 The calcium-magnesium (Ca2+-Mg2+) interaction in the process of nicotine-induced release of [3H]noradrenaline ([3H]NA) from rat isolated vas deferens was studied. Nicotine 64-72 arginine vasopressin Rattus norvegicus 137-140 22329817-3 2012 This study was carried out in the rat to investigate the effect of increasing doses of nicotine on subsets of magnocellular neurons containing either oxytocin or vasopressin. Nicotine 87-95 arginine vasopressin Rattus norvegicus 162-173 16204770-13 2005 CRH and vasopressin of the hypothalamic paraventricular nucleus may be involved in the nicotine induced alterations of HPA axis activity. Nicotine 87-95 arginine vasopressin Rattus norvegicus 8-19 21763305-1 2011 Centrally applied nicotine causes changes in blood pressure and vasopressin release. Nicotine 18-26 arginine vasopressin Rattus norvegicus 64-75 21763305-14 2011 It was concluded that for nicotine to release vasopressin, activation of both alpha4beta2 and alpha7 receptors is required. Nicotine 26-34 arginine vasopressin Rattus norvegicus 46-57 20117222-2 2010 We previously reported sexually diergic, dose-dependent HPA responses in vivo following nicotine administration: Male rats had greater arginine vasopressin (AVP) responses than females, and female rats had greater adrenocorticotropic hormone (ACTH) and corticosterone (CORT) responses than males. Nicotine 88-96 arginine vasopressin Rattus norvegicus 157-160 20117222-9 2010 Consistent with our in vivo and earlier in vitro studies, nicotine added to the hypothalamus tissue bath significantly increased HPA responses in a sex- and dose-dependent manner: Males had greater AVP responses than did females, and females had greater CRH responses than did males. Nicotine 58-66 arginine vasopressin Rattus norvegicus 198-201 18297099-1 2008 BACKGROUND AND PURPOSE: Central application of nicotine causes the release of vasopressin and affects blood pressure. Nicotine 47-55 arginine vasopressin Rattus norvegicus 78-89 10435011-7 1999 CONCLUSIONS: We conclude that in the conscious rat; (1) the pressor response to nicotine mainly depends on peripheral alpha-adrenergically-mediated vasoconstriction; (2) the vasomotor effect is caused by neural rather than adrenomedullary catecholamine release; (3) the nicotine-induced increase in heart rate (and presumably cardiac output) is per se unable to raise blood pressure, and (4) the nicotine-induced release of vasopressin plays no significant role in the pressor response. Nicotine 80-88 arginine vasopressin Rattus norvegicus 424-435 11234780-1 2001 Nicotine injected in the supraoptic nucleus facilitates vasopressin release from the neurohypophysis. Nicotine 0-8 arginine vasopressin Rattus norvegicus 56-67 11234780-8 2001 This presynaptic action may contribute, in part, to vasopressin release after nicotine. Nicotine 78-86 arginine vasopressin Rattus norvegicus 52-63 9387862-5 1997 A high level of signals for vasopressin mRNA was detected in the supraoptic nucleus after the animals were injected s.c. with nicotine. Nicotine 126-134 arginine vasopressin Rattus norvegicus 28-39 9387862-7 1997 Nicotine may up-regulate vasopressin gene expression in the supraoptic nucleus, acting through nicotinic acetylcholine receptors. Nicotine 0-8 arginine vasopressin Rattus norvegicus 25-36 7792061-4 1995 Both nicotine and cytisine caused a preferential release of vasopressin. Nicotine 5-13 arginine vasopressin Rattus norvegicus 60-71 8584207-4 1995 Microinfusion of nicotinic agonist, nicotine, to the SON also induced Fos expression, but mainly in the vasopressin neurons. Nicotine 36-44 arginine vasopressin Rattus norvegicus 104-115 1409734-6 1992 Microinjection of nicotine into the supraoptic nucleus at doses of 1 and 10 micrograms resulted in transient increases in the plasma vasopressin concentration that were 7-fold and 11-fold greater, respectively, than control values at 3 min. Nicotine 18-26 arginine vasopressin Rattus norvegicus 133-144 1504751-22 1992 We conclude that NSTX acts centrally on nicotinic cholinoceptors to block the release of vasopressin and oxytocin by nicotine and the release of vasopressin, but not that of oxytocin, by hypotension. Nicotine 117-125 arginine vasopressin Rattus norvegicus 89-100 1632621-0 1992 Vasopressin system is impaired in rat offspring prenatally exposed to chronic nicotine. Nicotine 78-86 arginine vasopressin Rattus norvegicus 0-11 19215455-5 1991 Treatment with the high dose of chronic nicotine alone decreased vasopressin content in and release from the neural lobe and its plasma concentration, but it did not change significantly the vasopressin content in the hypothalamus. Nicotine 40-48 arginine vasopressin Rattus norvegicus 65-76 19215455-6 1991 A similar pattern of changes in vasopressin release and plasma concentration, though less pronounced, was observed in the rats infused with the low dose of nicotine. Nicotine 156-164 arginine vasopressin Rattus norvegicus 32-43 19215455-7 1991 The withdrawal of the high dose of chronic nicotine gradually returned the decreased plasma vasopressin concentration, and its content in and release from the neural lobe to control values within 2 weeks. Nicotine 43-51 arginine vasopressin Rattus norvegicus 92-103 19215455-8 1991 However, vasopressin content in the hypothalamus started to decline 1 week after nicotine withdrawal and persisted to decline for at least 3 subsequent weeks. Nicotine 81-89 arginine vasopressin Rattus norvegicus 9-20 19215455-10 1991 The withdrawal of the low dose of nicotine exhibited a significant decline in plasma vasopressin concentration for up to 2 weeks only following chronic nicotine withdrawal, tending to return subsequently to control levels. Nicotine 34-42 arginine vasopressin Rattus norvegicus 85-96 19215455-10 1991 The withdrawal of the low dose of nicotine exhibited a significant decline in plasma vasopressin concentration for up to 2 weeks only following chronic nicotine withdrawal, tending to return subsequently to control levels. Nicotine 152-160 arginine vasopressin Rattus norvegicus 85-96