PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21596105-11	2011	The effects of nicotine persisted in P63 young adult brains which exhibited significantly downregulated GluR2, NR1, and NR2c expression levels in hippocampal homogenates and a considerably muted overall distribution of [3H]AMPA binding in areas CA1, CA2 and CA3, and the dentate gyrus.	Nicotine	15-23	carbonic anhydrase 3	Rattus norvegicus	258-261	
28029335-0	2017	Enhanced susceptibility of CA3 hippocampus to prenatal nicotine exposure.	Nicotine	55-63	carbonic anhydrase 3	Rattus norvegicus	27-30	
26164716-12	2015	Furthermore, nicotine increased alpha4beta2 nicotinic acetylcholine receptor density in the hippocampal CA3, dentate gyrus and perirhinal cortex in both saline- and methamphetamine-treated rats.	Nicotine	13-21	carbonic anhydrase 3	Rattus norvegicus	104-107	
28395994-7	2017	In rat hippocampal CA3-dentate gyrus synapses, nicotine-induced enhancement of long-term potentiation was also inhibited by thujone.	Nicotine	47-55	carbonic anhydrase 3	Rattus norvegicus	19-22	
28638710-10	2017	CONCLUSION: This study suggests that changes in DREAM protein expression in CA1, CA2, CA3, and DG regions of rat"s hippocampus and mean relative level of DREAM protein may involve in the mechanism of nicotine treatment-prevented REM sleep deprivation-induced learning and memory impairment in rats.	Nicotine	200-208	carbonic anhydrase 3	Rattus norvegicus	86-89	
28321180-3	2017	We explored multiple kinases by which nicotine can modulate gamma oscillations induced by kainate in rat hippocampal area CA3 in vitro.	Nicotine	38-46	carbonic anhydrase 3	Rattus norvegicus	122-125	
17330864-0	2007	Presynaptic calcium stores contribute to nicotine-elicited potentiation of evoked synaptic transmission at CA3-CA1 connections in the neonatal rat hippocampus.	Nicotine	41-49	carbonic anhydrase 3	Rattus norvegicus	107-114	
17174071-3	2007	failed to attenuate KA-induced neurotoxicity, repeated nicotine infusions (1.0 microg/side/day for 10 days) attenuated the seizures, the severe loss of cells in hippocampal regions CA1 and CA3, the increase in activator protein (AP)-1 DNA binding activity, and mortality after KA administration.	Nicotine	55-63	carbonic anhydrase 3	Rattus norvegicus	189-192	
20105181-8	2010	Furthermore, iontophoretic application of nicotine, AR-R17779 and PSAB-OFP each evoked current-dependent excitation of most CA3 pyramidal neurones studied, and this excitation was antagonized by co-iontophoretic application of MLA.	Nicotine	42-50	carbonic anhydrase 3	Rattus norvegicus	124-127	
16752811-6	2006	Nicotine administration increased the number of NADPH-diaphorase positive neurons in the CA3 area of the hippocampus and in the hilus of the dentate gyrus with no effect in the remaining areas studied.	Nicotine	0-8	carbonic anhydrase 3	Rattus norvegicus	89-92	
17223731-7	2007	In animals exposed only to nicotine the number of NADPH-diaphorase positive neurons in the CA3 area of the hippocampus and in the hilus of the dentate gyrus was higher than in controls.	Nicotine	27-35	carbonic anhydrase 3	Rattus norvegicus	91-94	
9832189-4	1998	Both Ach and nicotine produced NO signals ranging from 0.04 to 2.14 microM in the CA1, CA3, and dentate gyrus of the rat hippocampus that lasted for 2-5 min.	Nicotine	13-21	carbonic anhydrase 3	Rattus norvegicus	87-90	
11285026-6	2001	Similarly, acute nicotine significantly increased 5-HT(1A) receptor mRNA in the dentate gyrus (DG), CA3 and CA1 regions of the dorsal hippocampus 2 h and 24 h after injection.	Nicotine	17-25	carbonic anhydrase 3	Rattus norvegicus	100-103	
9697973-7	1998	CA3 pyramidal neurons showed significantly less apical dendritic thorny excrescence after gestational nicotine exposure.	Nicotine	102-110	carbonic anhydrase 3	Rattus norvegicus	0-3	
9697973-8	1998	Ultrastructurally the granule cells and the pyramidal neurons of the CA3 and CA1 regions showed increase in free ribosomes and dilatation of rough endoplasmic reticulum (RER) and Golgi apparatus cisternae in the nicotine-treated group.	Nicotine	212-220	carbonic anhydrase 3	Rattus norvegicus	69-72