PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9568854-7	1998	Changes in ERPF induced by nicotine were positively correlated with changes in urinary cyclic GMP.	Nicotine	27-35	5'-nucleotidase, cytosolic II	Homo sapiens	94-97	
9568854-8	1998	CONCLUSIONS: These findings indicate that nicotine administration is associated with renal vasoconstriction in healthy non-smokers, possibly through alteration of a cyclic-GMP-dependent vasoactive mechanism.	Nicotine	42-50	5'-nucleotidase, cytosolic II	Homo sapiens	172-175	
1356895-2	1992	We concluded from this project that electrical and chemical (by nicotine) stimulations evoke an increased influx of Ca2+ into nerve terminals and activate nitric oxide (NO) synthase, resulting in the synthesis and release of NO that stimulates the guanylate cyclase in smooth muscle, thereby causing the accumulation of cyclic GMP and eliciting muscle relaxation.	Nicotine	64-72	5'-nucleotidase, cytosolic II	Homo sapiens	327-330