PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2908045-2	1988	Nicotine was shown to produce significant increases in plasma AVP from 1.7 +/- 0.4 to 75.3 +/- 35.1 pg/ml (P less than .05) and in plasma ANF levels from 39 +/- 11 to 121 +/- 52 pg/ml (P less than .05) within 5 min of an i.v.	Nicotine	0-8	vasopressin-neurophysin 2-copeptin	Oryctolagus cuniculus	62-65	
2908045-9	1988	The increase in ANF plasma concentrations was probably due to a primary response to nicotine, for although exogenous AVP (1 microgram i.v.)	Nicotine	84-92	vasopressin-neurophysin 2-copeptin	Oryctolagus cuniculus	117-120	
2908045-12	1988	It was concluded that nicotine stimulates the secretion of AVP by activating central nicotinic projections to the hypothalamus.	Nicotine	22-30	vasopressin-neurophysin 2-copeptin	Oryctolagus cuniculus	59-62