PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32191315-2	2020	A series of metabolic and transport genes involved in the nicotine pathway are coordinately upregulated by a pair of jasmonate-responsive AP2/ERF-family transcription factors, NtERF189 and NtERF199, in the roots of Nicotiana tabacum (tobacco).	Nicotine	58-66	ethylene-responsive transcription factor RAP2-3-like	Nicotiana tabacum	138-141	
31727678-1	2020	APETALA2/ETHYLENE RESPONSE FACTOR (AP2/ERF) gene clusters regulate the biosynthesis of diverse specialized metabolites, including steroidal glycoalkaloids in tomato (Solanum lycopersicum) and potato (S. tuberosum), nicotine in tobacco (Nicotiana tabacum), and pharmaceutically valuable terpenoid indole alkaloids (TIAs) in Madagascar periwinkle (Catharanthus roseus).	Nicotine	215-223	ethylene-responsive transcription factor RAP2-3-like	Nicotiana tabacum	35-38	
31727678-8	2020	Moreover, overexpression of ORCA5 in tobacco and of NIC2 ERF189 in C. roseus hairy roots activates nicotine and TIA pathway genes, respectively, suggesting that the AP2/ERFs are functionally equivalent and are likely to be interchangeable.	Nicotine	99-107	ethylene-responsive transcription factor RAP2-3-like	Nicotiana tabacum	165-168	
31739571-3	2019	AP2/ERF and bHLH TFs work combinatorically to control nicotine biosynthesis and its subsequent accumulation in tobacco leaves.	Nicotine	54-62	ethylene-responsive transcription factor RAP2-3-like	Nicotiana tabacum	0-3	
31739571-2	2019	Nicotine biosynthesis is controlled developmentally and can be induced by abiotic and biotic stressors via a jasmonic acid (JA)-mediated signal transduction mechanism involving members of the APETALA 2/ethylene-responsive factor (AP2/ERF) and basic helix-loop-helix (bHLH) transcription factor (TF) families.	Nicotine	0-8	ethylene-responsive transcription factor RAP2-3-like	Nicotiana tabacum	230-237	
23934400-0	2014	NtERF32: a non-NIC2 locus AP2/ERF transcription factor required in jasmonate-inducible nicotine biosynthesis in tobacco.	Nicotine	87-95	ethylene-responsive transcription factor RAP2-3-like	Nicotiana tabacum	26-29	
21418355-2	2011	Here, we functionally characterized the JA-inducible tobacco (Nicotiana tabacum) AP2/ERF factor ORC1, one of the members of the NIC2-locus ERFs that control nicotine biosynthesis and a close homologue of ORCA3, a transcriptional activator of alkaloid biosynthesis in Catharanthus roseus.	Nicotine	157-165	ethylene-responsive transcription factor RAP2-3-like	Nicotiana tabacum	81-84