PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24830635-7 2014 Addition of nicotine to HFD further resulted in an increase in the incidence of hepatocellular apoptosis and was associated with activation of caspase 2, induction of inducible nitric oxide synthase (iNOS), and perturbation of the BAX/BCL-2 ratio. Nicotine 12-20 B cell leukemia/lymphoma 2 Mus musculus 235-240 15831280-8 2005 It was also shown that nicotine increases the mRNA level of bax and decreases that of bcl-2. Nicotine 23-31 B cell leukemia/lymphoma 2 Mus musculus 86-91 24481039-8 2014 As shown by our in vivo experiments, nicotine effectively ameliorated the impairment in spatial working memory induced by Abeta25-35; this was confirmed by a Morris water maze navigation test and further supported by the upregulation of Bcl-2 in the hippocampus of Abeta25-35-injected mice treated with nicotine. Nicotine 37-45 B cell leukemia/lymphoma 2 Mus musculus 237-242 24481039-8 2014 As shown by our in vivo experiments, nicotine effectively ameliorated the impairment in spatial working memory induced by Abeta25-35; this was confirmed by a Morris water maze navigation test and further supported by the upregulation of Bcl-2 in the hippocampus of Abeta25-35-injected mice treated with nicotine. Nicotine 303-311 B cell leukemia/lymphoma 2 Mus musculus 237-242