PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33355840-0	2021	Changes in mucin production in human airway epithelial cells after exposure to e-cigarette vapor with or without nicotine.	Nicotine	113-121	LOC100508689	Homo sapiens	11-16	
32368126-0	2020	Nicotine-Free e-Cigarette Vapor Exposure Stimulates IL6 and Mucin Production in Human Primary Small Airway Epithelial Cells.	Nicotine	0-8	LOC100508689	Homo sapiens	60-65	
32368126-9	2020	Conclusion: Our results suggest that human small airway epithelial cells exposed to nicotine-free e-vapor increase the inflammatory response and mucin production, which may contribute to distal lung airflow limitation and airway obstruction.	Nicotine	84-92	LOC100508689	Homo sapiens	145-150	
28974436-3	2017	Four small molecules (nicotine, mannitol, propranolol, caffeine) showed decreased permeability across mucin dispersions, compared to controls, and a greater effect was seen with HFDS than with PGM.	Nicotine	22-30	LOC100508689	Homo sapiens	102-107	
26025503-7	2015	In turn this allows lynx1 to limit the ability of nicotine to upregulate levels of mucin which is mediated by GABAergic signaling.	Nicotine	50-58	LOC100508689	Homo sapiens	83-88	
24838753-0	2014	Nicotine alters mucin rheological properties.	Nicotine	0-8	LOC100508689	Homo sapiens	16-21	
24838753-3	2014	We investigated whether nicotine can directly alter the rheological properties of mucin by examining its physicochemical interactions with human airway mucin gels secreted from A549 lung epithelial cells.	Nicotine	24-32	LOC100508689	Homo sapiens	82-87	
24838753-3	2014	We investigated whether nicotine can directly alter the rheological properties of mucin by examining its physicochemical interactions with human airway mucin gels secreted from A549 lung epithelial cells.	Nicotine	24-32	LOC100508689	Homo sapiens	152-157	
24838753-4	2014	Swelling kinetics and multiple particle tracking were utilized to assess mucin gel viscosity change when exposed to nicotine.	Nicotine	116-124	LOC100508689	Homo sapiens	73-78	
22923641-9	2012	Consistent with this, inhibition of Src signaling blocked the ability of the lynx1 knockdown to increase basal and nicotine-stimulated GABA(A)R and mucin mRNA expression.	Nicotine	115-123	LOC100508689	Homo sapiens	148-153	
10453373-1	1999	Our goal was to determine the effect of transdermal nicotine on cytokine and mucin gene transcription in ulcerative colitis (UC).	Nicotine	52-60	LOC100508689	Homo sapiens	77-82	
8869420-0	1996	Stimulation of colonic mucin synthesis by corticosteroids and nicotine.	Nicotine	62-70	LOC100508689	Homo sapiens	23-28	
8869420-3	1996	We have therefore compared the effects of corticosteroids including carbenoxolone, and nicotine on mucin synthesis, assessed by incorporation of N-[3H]acetylglucosamine into mucin by colonic epithelial biopsies in culture.	Nicotine	87-95	LOC100508689	Homo sapiens	99-104	
8869420-9	1996	Nicotine significantly increased mucin synthesis (180-220% of control values) between 62.5 nmol/l and 6.25 mumol/l (P < 0.05 at all concentrations) in both the right and left colon.	Nicotine	0-8	LOC100508689	Homo sapiens	33-38	
8869420-10	1996	In biopsies from the relatively uninvolved right colon of patients with ulcerative colitis, corticosteroids and nicotine caused relatively smaller increases in mucin synthesis.	Nicotine	112-120	LOC100508689	Homo sapiens	160-165	
8346498-10	1993	CONCLUSIONS: The results indicate that nicotine applied to the human airway mucosa produces pain and secretion of mucin, but inflammatory changes such as mucosal exudation of plasma and epithelial disruption may not be produced.	Nicotine	39-47	LOC100508689	Homo sapiens	114-119