PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33352448-0	2021	The intervention effect of nicotine on cervical fibroblast-myofibroblast differentiation in lipopolysaccharide-induced preterm birth model through activating the TGF-beta1/Smad3 pathway.	Nicotine	27-35	transforming growth factor, beta 1	Mus musculus	162-171	
35163704-5	2022	Stimulation-induced transforming growth factor-beta1 (TGF-beta1) production of iTreg cells was suppressed by nicotine, whereas interleukin (IL)-10 production and proliferation was not affected.	Nicotine	109-117	transforming growth factor, beta 1	Mus musculus	20-52	
35163704-5	2022	Stimulation-induced transforming growth factor-beta1 (TGF-beta1) production of iTreg cells was suppressed by nicotine, whereas interleukin (IL)-10 production and proliferation was not affected.	Nicotine	109-117	transforming growth factor, beta 1	Mus musculus	54-63	
33352448-14	2021	Nicotine improved pregnancy outcomes and inhibited collagen degradation, activated the TGF-beta1/Smad3 pathway and promoted cervical fibroblast-myofibroblast differentiation in PTB-like mice; such effects could be reversed by alpha-bungarotoxin (alpha-BGT).	Nicotine	0-8	transforming growth factor, beta 1	Mus musculus	87-96	
28440100-12	2017	CONCLUSIONS: Oral administration of nicotine significantly aggravated TAA-induced hepatic fibrosis in mice through enhancing TGF-beta secretion and TAA-induced oxidative stress.	Nicotine	36-44	transforming growth factor, beta 1	Mus musculus	125-133	
30114604-6	2018	Our results showed that the administration of nicotine reduced lung-tissue inflammation, the number of eosinophils in bronchoalveolar fluid, allergen-specific IgE and IL-4 production, while it increased the TGF-beta/IL-4 ratio and the number of Treg cells.	Nicotine	46-54	transforming growth factor, beta 1	Mus musculus	207-215	
24201082-5	2013	Moreover, nicotine was shown to down-regulate VEGF, PDGF and TGF-beta1 in both bone marrow derived macrophages and RAW 264.7 cells.	Nicotine	10-18	transforming growth factor, beta 1	Mus musculus	61-70	
24201082-2	2013	Nicotine injection in full-thickness excisional skin wounds minimally affected inflammatory mediators like TNF, IL-6 and IL-12 while it induced a down-regulation in the expression of growth factors like VEGF, PDGF, TGF-beta1 and TGF-beta2, and the anti-inflammatory cytokine IL-10.	Nicotine	0-8	transforming growth factor, beta 1	Mus musculus	215-224	
22562289-5	2012	RESULTS: In utero nicotine increased interleukin-13 and transforming growth factor-beta1 (TGFbeta1) in the neonatal lung.	Nicotine	18-26	transforming growth factor, beta 1	Mus musculus	56-88	
22562289-5	2012	RESULTS: In utero nicotine increased interleukin-13 and transforming growth factor-beta1 (TGFbeta1) in the neonatal lung.	Nicotine	18-26	transforming growth factor, beta 1	Mus musculus	90-98	
22562289-6	2012	Nicotine-exposed AMs demonstrated increased TGFbeta1 and increased markers of alternative activation with diminished phagocytic function.	Nicotine	0-8	transforming growth factor, beta 1	Mus musculus	44-52