PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35216385-0 2022 VPA and TSA Interrupt the Interplay between mutp53 and HSP70, Leading to CHK1 and RAD51 Down-Regulation and Sensitizing Pancreatic Cancer Cells to AZD2461 PARP Inhibitor. trichostatin A 8-11 RAD51 recombinase Homo sapiens 82-87 35216385-4 2022 At a molecular level, VPA and TSA down-regulated CHK1 and RAD51, which is correlated with the interruption of the cross-talk between mutp53 and HSP70. trichostatin A 30-33 RAD51 recombinase Homo sapiens 58-63 35216385-5 2022 Moreover, VPA and to a lesser extent TSA reactivated wtp53 in these cells, which contributed to CHK1 and RAD51 reduction. trichostatin A 37-40 RAD51 recombinase Homo sapiens 105-110