PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8548298-3 1995 Relative to bovine serum albumin (BSA) or Cytochrome C treatments, NGF treatment facilitated acquisition and prolonged extinction of a lithium chloride (LiCl)-induced saccharin aversion. Lithium Chloride 135-151 nerve growth factor Rattus norvegicus 67-70 8874536-1 1996 To understand the mechanism underlying the neurotoxicity of lithium ion, we investigated the inhibition of the nerve growth factor-induced neuronal differentiation of rat PC12 pheochromocytoma cells induced by treatment with LiCl. Lithium Chloride 225-229 nerve growth factor Rattus norvegicus 111-130 8874536-2 1996 Incubation with 0.1-3 mM LiCl from 30 min before nerve growth factor (NGF) treatment attenuated neurite outgrowth. Lithium Chloride 25-29 nerve growth factor Rattus norvegicus 49-68 8874536-2 1996 Incubation with 0.1-3 mM LiCl from 30 min before nerve growth factor (NGF) treatment attenuated neurite outgrowth. Lithium Chloride 25-29 nerve growth factor Rattus norvegicus 70-73 8874536-6 1996 These observations, that chronic treatment with LiCl inhibits the NGF-induced neuronal differentiation in a transcription-dependent manner and inhibits phosphoinositide metabolism, suggest a possible causal relationship between these two events. Lithium Chloride 48-52 nerve growth factor Rattus norvegicus 66-69 8548298-3 1995 Relative to bovine serum albumin (BSA) or Cytochrome C treatments, NGF treatment facilitated acquisition and prolonged extinction of a lithium chloride (LiCl)-induced saccharin aversion. Lithium Chloride 153-157 nerve growth factor Rattus norvegicus 67-70 2843607-5 1988 After incubation for 20 h with NGF, an increased binding of [3H]BK to the PC12 (+) cells was observed at 4 degrees C. Exposure of the cells for 30 min to 25 mM LiCl enhanced the effect of BK on the inositol incorporation into total inositol lipids, especially in PC12(+) cells. Lithium Chloride 160-164 nerve growth factor Rattus norvegicus 31-34 25576342-7 2015 This was paralleled by a significant upregulation of NGF protein and mRNA in the vehicle-treated rats, which was reduced after administering either LiCl, SB216763, or combination. Lithium Chloride 148-152 nerve growth factor Rattus norvegicus 53-56 2843608-1 1988 LiCl stimulated the formation of inositol monophosphate in PC12 cells that had been exposed to nerve growth factor (NGF) for 4-5 days. Lithium Chloride 0-4 nerve growth factor Rattus norvegicus 95-114 2843608-1 1988 LiCl stimulated the formation of inositol monophosphate in PC12 cells that had been exposed to nerve growth factor (NGF) for 4-5 days. Lithium Chloride 0-4 nerve growth factor Rattus norvegicus 116-119 2843608-4 1988 With membranes isolated from PC12 cells differentiated with NGF, the hydrolysis of added phosphatidylinositol 4,5-bisphosphate (PIP2) was stimulated by LiCl in a biphasic manner, with the first stimulation half-maximal at approximately 0.7 mM and the second half-maximal at approximately 15 mM LiCl. Lithium Chloride 152-156 nerve growth factor Rattus norvegicus 60-63 2843608-4 1988 With membranes isolated from PC12 cells differentiated with NGF, the hydrolysis of added phosphatidylinositol 4,5-bisphosphate (PIP2) was stimulated by LiCl in a biphasic manner, with the first stimulation half-maximal at approximately 0.7 mM and the second half-maximal at approximately 15 mM LiCl. Lithium Chloride 294-298 nerve growth factor Rattus norvegicus 60-63 4030895-1 1985 LiCl (2.5-20 mM) reversibly suppressed nerve growth factor (NGF)-induced neurite outgrowth by cultured rat PC 12 pheochromocytoma cells. Lithium Chloride 0-4 nerve growth factor Rattus norvegicus 39-58 4030895-1 1985 LiCl (2.5-20 mM) reversibly suppressed nerve growth factor (NGF)-induced neurite outgrowth by cultured rat PC 12 pheochromocytoma cells. Lithium Chloride 0-4 nerve growth factor Rattus norvegicus 60-63 4030895-2 1985 Similar concentrations of LiCl also reversibly blocked NGF-dependent regeneration of neurites by PC12 cells that had been primed by long-term pre-exposure to NGF and by cultured newborn mouse sympathetic neurons. Lithium Chloride 26-30 nerve growth factor Rattus norvegicus 55-58 4030895-2 1985 Similar concentrations of LiCl also reversibly blocked NGF-dependent regeneration of neurites by PC12 cells that had been primed by long-term pre-exposure to NGF and by cultured newborn mouse sympathetic neurons. Lithium Chloride 26-30 nerve growth factor Rattus norvegicus 158-161