PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19010416-8 2009 Since IL-1beta is an etiologic trigger for BBB breakdown and its serum elevation occurs before onset of SE early after LiCl and pilocarpine injections, we tested the hypothesis that intravenous administration of IL-1 receptor antagonists (IL-1ra) may prevent pilocarpine-induced seizures. Lithium Chloride 119-123 interleukin 1 receptor antagonist Homo sapiens 212-237 8221116-4 1993 The present experiments report that IL-1 can itself produce hyperalgesia as assessed by tailflick to radiant heat, and that recombinant IL-1ra blocks the hyperalgesia produced by LiCl and LPS. Lithium Chloride 179-183 interleukin 1 receptor antagonist Homo sapiens 136-142