PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28827764-6	2017	NOX complexes increased endosomal ROS levels that were permeable into cytoplasm, leading to NF-kappaB-mediated ICAM1 up-regulation.	nicotine 1-N-oxide	0-3	intercellular adhesion molecule 1	Homo sapiens	111-116	
25591777-7	2015	CONCLUSION: This study reports that elevated levels of ketones upregulate NOX, contributing to increased oxidative stress, ICAM-1 levels, and cellular dysfunction.	nicotine 1-N-oxide	74-77	intercellular adhesion molecule 1	Homo sapiens	123-129