PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7517798-3	1994	METHODS AND RESULTS: We studied the effect of human recombinant interleukin-1 beta (IL-1 beta) on synthesis of NO2-/NO3- (NOx) and the expression of NOS mRNA and protein in cultured neonatal rat cardiocytes.	nicotine 1-N-oxide	122-125	interleukin 1 beta	Homo sapiens	64-82	
7517798-3	1994	METHODS AND RESULTS: We studied the effect of human recombinant interleukin-1 beta (IL-1 beta) on synthesis of NO2-/NO3- (NOx) and the expression of NOS mRNA and protein in cultured neonatal rat cardiocytes.	nicotine 1-N-oxide	122-125	interleukin 1 beta	Homo sapiens	84-93	
28875725-0	2018	IL-1beta haplotype influences the effect of NOx exposure on gestational age in the South African MACE birth cohort.	nicotine 1-N-oxide	44-47	interleukin 1 beta	Homo sapiens	0-8	
28875725-3	2018	The aim of this study was to determine the association between the maternal interleukin-1beta (IL-1beta) haplotype and expression variation with oxides of nitrogen (NOx) levels, and thereafter investigate the IL-1beta haplotype-specific effects of NOx exposure levels, IL-1beta mRNA expression and other variables on gestational age.	nicotine 1-N-oxide	165-168	interleukin 1 beta	Homo sapiens	76-93	
28088327-9	2017	Thus, IL-1beta c-Src and IL-1beta NOX signaling pathways appear to be responsible for the production of cellular and mitochondrial ROS in CFTR-KD cells.	nicotine 1-N-oxide	34-37	interleukin 1 beta	Homo sapiens	6-14	
28875725-3	2018	The aim of this study was to determine the association between the maternal interleukin-1beta (IL-1beta) haplotype and expression variation with oxides of nitrogen (NOx) levels, and thereafter investigate the IL-1beta haplotype-specific effects of NOx exposure levels, IL-1beta mRNA expression and other variables on gestational age.	nicotine 1-N-oxide	165-168	interleukin 1 beta	Homo sapiens	95-103	
28875725-9	2018	RESULTS: IL-1beta mRNA expression was found to possess a haplotype-dependent effect ( p = 0.0001) and its expression levels positively correlated with NOx levels ( r = 0.34; p = 0.006).	nicotine 1-N-oxide	151-154	interleukin 1 beta	Homo sapiens	9-17	
28875725-13	2018	CONCLUSION: These data have implications for better understanding the effect of prenatal NOx exposure on gestational age and demonstrate the role of the IL-1beta haplotype in modulating the effects of NOx exposure.	nicotine 1-N-oxide	201-204	interleukin 1 beta	Homo sapiens	153-161	
28088327-9	2017	Thus, IL-1beta c-Src and IL-1beta NOX signaling pathways appear to be responsible for the production of cellular and mitochondrial ROS in CFTR-KD cells.	nicotine 1-N-oxide	34-37	interleukin 1 beta	Homo sapiens	25-33	
28078290-3	2016	Elevated NO x level was observed in patients who received the first-line disease-modifying therapy (interferons beta-1a and beta-1b) in comparison with the subjects treated with the second-line disease-modifying therapy (natalizumab; fingolimod) and healthy controls without significant differences in C-reactive protein and interleukin-1 beta.	nicotine 1-N-oxide	9-13	interleukin 1 beta	Homo sapiens	325-343	
27614934-0	2016	Corrigendum to "Angiotensin(1-7) attenuated angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H2O2-activated NLRP3 inflammasome/IL-1beta/Smad circuit": [Free Radic.	nicotine 1-N-oxide	96-99	interleukin 1 beta	Homo sapiens	142-150	
25050325-6	2014	TNFalpha and IL-1beta provoked rapid, NOX-mediated generation of ROS in advancing growth cones, which preceded paralysis of motility and collapse of morphology.	nicotine 1-N-oxide	38-41	interleukin 1 beta	Homo sapiens	13-21	
10642306-5	2000	For this, we measured IL-1beta-stimulated nitrite (NOx) production with use of the Griess reagent, prostaglandin E(2) (PGE(2)) production with use of an enzyme immunoassay, and arachidonic acid release in the presence and absence of BEL.	nicotine 1-N-oxide	51-54	interleukin 1 beta	Homo sapiens	22-30	
10642306-7	2000	Treatment with IL-1beta (5 ng/mL) for 24 hours stimulated NOx production by 8-fold and iNOS protein levels by at least 10-fold.	nicotine 1-N-oxide	58-61	interleukin 1 beta	Homo sapiens	15-23	
10642306-10	2000	BEL inhibited IL-1beta-stimulated NOx production and iNOS protein by 88% and 93%, respectively.	nicotine 1-N-oxide	34-37	interleukin 1 beta	Homo sapiens	14-22