PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25239655-2	2014	NOS3 and NOS2 SNPs might modify plasma nitrite/nitrate (NOx) levels, sepsis development, hemodynamics and survival.	nicotine 1-N-oxide	56-59	nitric oxide synthase 3	Homo sapiens	0-4	
25320160-9	2015	CONCLUSION: We could replicate and extend previous findings showing altered NOx (-) levels in BPD and an influence of NOS3 rs2070744 on NOS3 expression and NOx (-) concentration.	nicotine 1-N-oxide	76-79	nitric oxide synthase 3	Homo sapiens	118-122	
25320160-9	2015	CONCLUSION: We could replicate and extend previous findings showing altered NOx (-) levels in BPD and an influence of NOS3 rs2070744 on NOS3 expression and NOx (-) concentration.	nicotine 1-N-oxide	156-159	nitric oxide synthase 3	Homo sapiens	118-122	
25239655-8	2014	Plasma NOx was higher in carriers of the T allele of the NOS3 (E298D) SNP (p = 0.006).	nicotine 1-N-oxide	7-10	nitric oxide synthase 3	Homo sapiens	57-61	
16007000-1	2005	OBJECTIVES: Controversy exists regarding the effects of polymorphisms in the endothelial nitric oxide synthase (eNOS) gene on nitrites/nitrates (NOx) plasma concentrations.	nicotine 1-N-oxide	145-148	nitric oxide synthase 3	Homo sapiens	77-110	
16007000-1	2005	OBJECTIVES: Controversy exists regarding the effects of polymorphisms in the endothelial nitric oxide synthase (eNOS) gene on nitrites/nitrates (NOx) plasma concentrations.	nicotine 1-N-oxide	145-148	nitric oxide synthase 3	Homo sapiens	112-116	
16007000-2	2005	In this study we compared the distribution of haplotypes involving three relevant eNOS polymorphisms (T-786C in the promoter region; b/a in intron 4, and Glu298Asp in exon 7) in healthy subjects with low and high circulating NOx levels.	nicotine 1-N-oxide	225-228	nitric oxide synthase 3	Homo sapiens	82-86	
16007000-10	2005	The frequencies of the remaining haplotypes were not different among group L and H. CONCLUSIONS: While eNOS genotypes are not significantly associated with changes in the circulating NOx concentrations, the specific eNOS haplotype that includes the "C", "4b", and "Glu" alleles is associated with lower circulating NOx concentrations.	nicotine 1-N-oxide	315-318	nitric oxide synthase 3	Homo sapiens	216-220	
11017941-3	2000	The aims of this study were to examine plasma NOx in patients with coronary artery disease (CAD) and to assess the association between plasma NOx concentrations and the three ecNOS gene polymorphisms.	nicotine 1-N-oxide	142-145	nitric oxide synthase 3	Homo sapiens	175-180	
9409304-6	1997	The results of the variance component linkage analysis were consistent with linkage of a quantitative trait locus in or near the ecNOS gene to variation in plasma NOx levels (P = .0066).	nicotine 1-N-oxide	163-166	nitric oxide synthase 3	Homo sapiens	129-134	
9409304-7	1997	While many environmental factors have been shown to alter transiently plasma NOx levels, our study is the first to identify a substantial effect of the ecNOS locus on the variance of plasma NOx, i.e. basal NO production.	nicotine 1-N-oxide	77-80	nitric oxide synthase 3	Homo sapiens	152-157	
9409304-7	1997	While many environmental factors have been shown to alter transiently plasma NOx levels, our study is the first to identify a substantial effect of the ecNOS locus on the variance of plasma NOx, i.e. basal NO production.	nicotine 1-N-oxide	190-193	nitric oxide synthase 3	Homo sapiens	152-157	
24944642-8	2014	In addition, the plasma NOx concentration in the eNOS Glu/Glu homozygote carriers (129.66+-59.15 mumol/l) was significantly lower compared with the Asp allele carriers (169.84+- 55.18 mumol/l; P=0.010).	nicotine 1-N-oxide	24-27	nitric oxide synthase 3	Homo sapiens	49-53	
24748593-2	2014	The present study was designed to evaluate the relationship between exercise training and NOS3 polymorphisms at -786T>C, 894G>T, and intron 4b/a on blood pressure (BP) using 24-h ambulatory BP monitoring (ABPM), nitrate/nitrite levels (NOx), and redox state.	nicotine 1-N-oxide	242-245	nitric oxide synthase 3	Homo sapiens	90-94	
24748593-10	2014	The NOS3 polymorphism for intron 4 mitigated the beneficial effect of ET for systolic BP (nonpolymorphic group: -3.0% and polymorphic group: -0.6%) and diastolic BP (nonpolymorphic group: -3.2% and polymorphic group: -0.5%), but it was not associated with NOx level and redox state.	nicotine 1-N-oxide	256-259	nitric oxide synthase 3	Homo sapiens	4-8