PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17191118-0 2007 The role of PKCzeta in amikacin-induced apoptosis in the cochlea: prevention by aspirin. Aspirin 80-87 protein kinase C zeta Homo sapiens 12-19 17191118-8 2007 Prior treatment with aspirin prevented PKCzeta cleavage and nuclear translocation. Aspirin 21-28 protein kinase C zeta Homo sapiens 39-46 16547586-0 2006 The role of PKCzeta in NMDA-induced retinal ganglion cell death: prevention by aspirin. Aspirin 79-86 protein kinase C zeta Homo sapiens 12-19 16547586-4 2006 PKCzeta regulates the NF-kappaB pathway in cellular responses to various stresses and we have shown that aspirin inhibits purified human PKCzeta. Aspirin 105-112 protein kinase C zeta Homo sapiens 0-7 16547586-4 2006 PKCzeta regulates the NF-kappaB pathway in cellular responses to various stresses and we have shown that aspirin inhibits purified human PKCzeta. Aspirin 105-112 protein kinase C zeta Homo sapiens 137-144 16547586-9 2006 We also found that pretreatment with aspirin or the coinjection of NMDA with a specific PKCzeta inhibitor counteracted the effects of NMDA. Aspirin 37-44 protein kinase C zeta Homo sapiens 88-95 15935075-3 2005 We show here that aspirin exerts at least some of its effects through PKCzeta, decreasing the NMDA-induced activation, cleavage and nuclear translocation of this molecule. Aspirin 18-25 protein kinase C zeta Homo sapiens 70-77 15935075-4 2005 Aspirin (acetylsalicylic acid) directly inhibited the protein kinase activity of PKCzeta, whereas salicylic acid did not. Aspirin 0-7 protein kinase C zeta Homo sapiens 81-88 15935075-4 2005 Aspirin (acetylsalicylic acid) directly inhibited the protein kinase activity of PKCzeta, whereas salicylic acid did not. Aspirin 9-29 protein kinase C zeta Homo sapiens 81-88 15935075-5 2005 This direct effect of aspirin on purified human PKCzeta is consistent with PKCzeta inhibition preventing the NMDA-induced death of cortical neurones. Aspirin 22-29 protein kinase C zeta Homo sapiens 48-55 15935075-5 2005 This direct effect of aspirin on purified human PKCzeta is consistent with PKCzeta inhibition preventing the NMDA-induced death of cortical neurones. Aspirin 22-29 protein kinase C zeta Homo sapiens 75-82 15935075-8 2005 Aspirin protects cells against NMDA-induced apoptosis by means of a novel mechanism targeting PKCzeta, a key molecule in inflammatory responses and neurodegeneration. Aspirin 0-7 protein kinase C zeta Homo sapiens 94-101