PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23400363-1	2013	In the present study, we investigate the in vitro effect of hypoxanthine on acetylcholinesterase and butyrylcholinesterase activities in the hippocampus, striatum, cerebral cortex and serum of 15-, 30- and 60-day-old rats.	Hypoxanthine	60-72	acetylcholinesterase	Rattus norvegicus	76-96	
23400363-5	2013	Hypoxanthine (10.0 muM), when added to the incubation medium, enhanced acetylcholinesterase activity in the hippocampus and striatum of 15- and 30-day-old rats and reduced butyrylcholinesterase activity in the serum of 60-day-old rats.	Hypoxanthine	0-12	acetylcholinesterase	Rattus norvegicus	71-91	
17034984-0	2006	Intrastriatal hypoxanthine administration affects Na+,K+-ATPase, acetylcholinesterase and catalase activities in striatum, hippocampus and cerebral cortex of rats.	Hypoxanthine	14-26	acetylcholinesterase	Rattus norvegicus	65-85	
17034984-1	2006	The aim of this study was to investigate the effects of a single intrastriatal injection of hypoxanthine, the major metabolite accumulating in Lesch-Nyhan disease, on Na(+),K(+)-ATPase, acetylcholinesterase and catalase activities in striatum, cerebral cortex and hippocampus of rats at different post-infusion periods.	Hypoxanthine	92-104	acetylcholinesterase	Rattus norvegicus	186-206	
17034984-5	2006	Results show regional and time dependent effects of hypoxanthine on Na(+),K(+)-ATPase, acetylcholinesterase and catalase activities.	Hypoxanthine	52-64	acetylcholinesterase	Rattus norvegicus	87-107	
17034984-8	2006	We suggest that these modification on cerebral biochemical parameters (Na(+),K(+)-ATPase, acetylcholinesterase and catalase activities) induced by intrastriatal administration of hypoxanthine in all cerebral structures studied, striatum, hippocampus and cerebral cortex, could be involved in the pathophysiology of Lesch-Nyhan disease.	Hypoxanthine	179-191	acetylcholinesterase	Rattus norvegicus	90-110