PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27168850-0	2016	Chlorogenic acid induces apoptosis to inhibit inflammatory proliferation of IL-6-induced fibroblast-like synoviocytes through modulating the activation of JAK/STAT and NF-kappaB signaling pathways.	Chlorogenic Acid	0-16	nuclear factor kappa B subunit 1	Homo sapiens	168-177	
34216581-0	2021	Beneficial effects of chlorogenic acid treatment on neuroinflammation after deep hypothermic circulatory arrest may be mediated through CYLD/NF-kappaB signaling.	Chlorogenic Acid	22-38	nuclear factor kappa B subunit 1	Homo sapiens	141-150	
35437426-0	2022	Chlorogenic Acid as a Positive Regulator in LPS-PG-Induced Inflammation via TLR4/MyD88-Mediated NF-kappaB and PI3K/MAPK Signaling Cascades in Human Gingival Fibroblasts.	Chlorogenic Acid	0-16	nuclear factor kappa B subunit 1	Homo sapiens	96-105	
35289676-4	2022	Chlorogenic acid (CGA), curcumin (CUR), epigallocatechin gallate (EGCG), and resveratrol (RSV) can act as antioxidants that activate AMP-activated protein kinase (AMPK) to downregulate ROS, and as prooxidants to generate ROS, leading to the downregulation of NF-kappaB.	Chlorogenic Acid	0-16	nuclear factor kappa B subunit 1	Homo sapiens	259-268	
33639350-8	2021	Moreover, pretreatment with baicalein and chlorogenic acid significantly inhibited NF-kappaB activation, and this inhibited the subsequent production of the proinflammatory cytokines TNF-alpha and IL-1beta in the context of IBDV infection.	Chlorogenic Acid	42-58	nuclear factor kappa B subunit 1	Homo sapiens	83-92	
32882585-6	2020	We also discovered that chlorogenic acid inhibits the binding of annexin A2 to p50 subunit thereby inhibiting the expression of downstream anti-apoptotic genes cIAP1 and cIAP2 of the NF-kappaB signaling pathway in A549 cells in vitro and in vivo.	Chlorogenic Acid	24-40	nuclear factor kappa B subunit 1	Homo sapiens	79-82	
32882585-6	2020	We also discovered that chlorogenic acid inhibits the binding of annexin A2 to p50 subunit thereby inhibiting the expression of downstream anti-apoptotic genes cIAP1 and cIAP2 of the NF-kappaB signaling pathway in A549 cells in vitro and in vivo.	Chlorogenic Acid	24-40	nuclear factor kappa B subunit 1	Homo sapiens	183-192	
32882585-8	2020	Thus, this work demonstrates that chlorogenic acid binds annexin A2, causing a decrease in the expression of NF-kappaB downstream anti-apoptotic genes, and inhibiting the proliferation of A549 cells in vivo and in vitro.	Chlorogenic Acid	34-50	nuclear factor kappa B subunit 1	Homo sapiens	109-118	
31240234-0	2019	Chlorogenic Acid Inhibits BAFF Expression in Collagen-Induced Arthritis and Human Synoviocyte MH7A Cells by Modulating the Activation of the NF-kappaB Signaling Pathway.	Chlorogenic Acid	0-16	nuclear factor kappa B subunit 1	Homo sapiens	141-150	
19937041-8	2010	We also observed that chlorogenic acid attenuated or blocked IL-1beta-induced nuclear translocation of nuclear factor-kappaB subunits p50 and p65, which in turn attenuated CAM expression at the transcription level.	Chlorogenic Acid	22-38	nuclear factor kappa B subunit 1	Homo sapiens	134-137