PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33639350-8 2021 Moreover, pretreatment with baicalein and chlorogenic acid significantly inhibited NF-kappaB activation, and this inhibited the subsequent production of the proinflammatory cytokines TNF-alpha and IL-1beta in the context of IBDV infection. Chlorogenic Acid 42-58 interleukin 1 alpha Homo sapiens 197-205 32726040-5 2020 The results showed that the lower the concentration of chlorogenic acid, the higher the inhibition rate of Jun N-terminal kinase(JNK) at downstream of IL-1 by the combination of chlorogenic acid and linalool; the higher the concentration of luteolin in IL-6 pathway, the higher the inhibition rate of C-reactive protein(CRP) at downstream of IL-6 by the combination of chlorogenic acid and luteolin. Chlorogenic Acid 55-71 interleukin 1 alpha Homo sapiens 151-155 32726040-5 2020 The results showed that the lower the concentration of chlorogenic acid, the higher the inhibition rate of Jun N-terminal kinase(JNK) at downstream of IL-1 by the combination of chlorogenic acid and linalool; the higher the concentration of luteolin in IL-6 pathway, the higher the inhibition rate of C-reactive protein(CRP) at downstream of IL-6 by the combination of chlorogenic acid and luteolin. Chlorogenic Acid 178-194 interleukin 1 alpha Homo sapiens 151-155 32726040-5 2020 The results showed that the lower the concentration of chlorogenic acid, the higher the inhibition rate of Jun N-terminal kinase(JNK) at downstream of IL-1 by the combination of chlorogenic acid and linalool; the higher the concentration of luteolin in IL-6 pathway, the higher the inhibition rate of C-reactive protein(CRP) at downstream of IL-6 by the combination of chlorogenic acid and luteolin. Chlorogenic Acid 178-194 interleukin 1 alpha Homo sapiens 151-155 32726040-6 2020 It revealed that the potential efficacy markers of Lonicerae Japonicae Flos in heat-clearing and detoxifying effect based on IL-1 signaling pathway were chlorogenic acid and linalool, and the potential efficacy markers of Lonicerae Japonicae Flos in heat-clearing and detoxifying effect based on IL-6 signaling pathway were chlorogenic acid and luteolin. Chlorogenic Acid 153-169 interleukin 1 alpha Homo sapiens 125-129 33142463-5 2020 Besides, the expression level of IL-1beta mRNA showed significant increase during dihydromyricetin, chlorogenic acid, naringin, imiquimod, thymopentin, beta-D-Glucan, astragalus polysacharin, astragalus saponin I, astragalus flavone, curcumin, CpG-DNA-2, and LPS treatment. Chlorogenic Acid 100-116 interleukin 1 alpha Homo sapiens 33-41 33164356-4 2020 The results showed that adenosine, epigoitrin, chlorogenic acid, caffeic acid, cichoric acid, corynoline, baicalin, wogonoside, wogonin and oroxylin A had a certain regulatory effect on inflammatory factor tumor necrosis factor(TNF-alpha), interleukin(IL-1beta) and IL-6 at specific concentrations in a dose-dependent manner. Chlorogenic Acid 47-63 interleukin 1 alpha Homo sapiens 240-260