PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27104513-8	2016	Gallic acid and chlorogenic acid could suppress the release of pro-inflammatory cytokine IL-6 and chemokine CCL7 and CXCL8, respectively, in IL-31- and IL-33-treated eosinophils-dermal fibroblasts co-culture; while berberine could suppress the release of IL-6, CXCL8, CCL2 and CCL7 in the eosinophil culture and eosinophils-dermal fibroblasts co-culture (all p < 0.05).	Chlorogenic Acid	16-32	interleukin 6	Homo sapiens	89-93	
27168850-0	2016	Chlorogenic acid induces apoptosis to inhibit inflammatory proliferation of IL-6-induced fibroblast-like synoviocytes through modulating the activation of JAK/STAT and NF-kappaB signaling pathways.	Chlorogenic Acid	0-16	interleukin 6	Homo sapiens	76-80	
27104513-8	2016	Gallic acid and chlorogenic acid could suppress the release of pro-inflammatory cytokine IL-6 and chemokine CCL7 and CXCL8, respectively, in IL-31- and IL-33-treated eosinophils-dermal fibroblasts co-culture; while berberine could suppress the release of IL-6, CXCL8, CCL2 and CCL7 in the eosinophil culture and eosinophils-dermal fibroblasts co-culture (all p < 0.05).	Chlorogenic Acid	16-32	interleukin 6	Homo sapiens	255-259	
23336518-3	2013	The results showed that chlorogenic acid, 3, 4-dicaffeoylquinic acid, 3, 5-dicaffeoylquinic acid and 4, 5-dicaffeoylquinic acid significantly inhibited the prostaglandin E(2) (PGE(2)) release and reversed the interleukin-6 (IL-6) secretion of macrophages (p < 0.05).	Chlorogenic Acid	24-40	interleukin 6	Homo sapiens	209-222	
23336518-3	2013	The results showed that chlorogenic acid, 3, 4-dicaffeoylquinic acid, 3, 5-dicaffeoylquinic acid and 4, 5-dicaffeoylquinic acid significantly inhibited the prostaglandin E(2) (PGE(2)) release and reversed the interleukin-6 (IL-6) secretion of macrophages (p < 0.05).	Chlorogenic Acid	24-40	interleukin 6	Homo sapiens	224-228	
32726040-5	2020	The results showed that the lower the concentration of chlorogenic acid, the higher the inhibition rate of Jun N-terminal kinase(JNK) at downstream of IL-1 by the combination of chlorogenic acid and linalool; the higher the concentration of luteolin in IL-6 pathway, the higher the inhibition rate of C-reactive protein(CRP) at downstream of IL-6 by the combination of chlorogenic acid and luteolin.	Chlorogenic Acid	55-71	interleukin 6	Homo sapiens	253-257	
12022439-2	2002	Chlorogenic acid, a plant polyphenol, inhibited SE-induced T-cell proliferation (by 98%) and production of interleukin 1beta, tumor necrosis factor, interleukin 6, interferon gamma, monocyte chemotactic protein I (MCP-l), macrophage inflammatory protein (MIP)-lalpha, and MIP-lbeta by human peripheral blood mononuclear cells.	Chlorogenic Acid	0-16	interleukin 6	Homo sapiens	149-162	
33164356-4	2020	The results showed that adenosine, epigoitrin, chlorogenic acid, caffeic acid, cichoric acid, corynoline, baicalin, wogonoside, wogonin and oroxylin A had a certain regulatory effect on inflammatory factor tumor necrosis factor(TNF-alpha), interleukin(IL-1beta) and IL-6 at specific concentrations in a dose-dependent manner.	Chlorogenic Acid	47-63	interleukin 6	Homo sapiens	266-270	
32726040-5	2020	The results showed that the lower the concentration of chlorogenic acid, the higher the inhibition rate of Jun N-terminal kinase(JNK) at downstream of IL-1 by the combination of chlorogenic acid and linalool; the higher the concentration of luteolin in IL-6 pathway, the higher the inhibition rate of C-reactive protein(CRP) at downstream of IL-6 by the combination of chlorogenic acid and luteolin.	Chlorogenic Acid	55-71	interleukin 6	Homo sapiens	342-346	
32726040-5	2020	The results showed that the lower the concentration of chlorogenic acid, the higher the inhibition rate of Jun N-terminal kinase(JNK) at downstream of IL-1 by the combination of chlorogenic acid and linalool; the higher the concentration of luteolin in IL-6 pathway, the higher the inhibition rate of C-reactive protein(CRP) at downstream of IL-6 by the combination of chlorogenic acid and luteolin.	Chlorogenic Acid	178-194	interleukin 6	Homo sapiens	253-257	
32726040-5	2020	The results showed that the lower the concentration of chlorogenic acid, the higher the inhibition rate of Jun N-terminal kinase(JNK) at downstream of IL-1 by the combination of chlorogenic acid and linalool; the higher the concentration of luteolin in IL-6 pathway, the higher the inhibition rate of C-reactive protein(CRP) at downstream of IL-6 by the combination of chlorogenic acid and luteolin.	Chlorogenic Acid	178-194	interleukin 6	Homo sapiens	342-346	
32726040-5	2020	The results showed that the lower the concentration of chlorogenic acid, the higher the inhibition rate of Jun N-terminal kinase(JNK) at downstream of IL-1 by the combination of chlorogenic acid and linalool; the higher the concentration of luteolin in IL-6 pathway, the higher the inhibition rate of C-reactive protein(CRP) at downstream of IL-6 by the combination of chlorogenic acid and luteolin.	Chlorogenic Acid	178-194	interleukin 6	Homo sapiens	253-257	
32726040-5	2020	The results showed that the lower the concentration of chlorogenic acid, the higher the inhibition rate of Jun N-terminal kinase(JNK) at downstream of IL-1 by the combination of chlorogenic acid and linalool; the higher the concentration of luteolin in IL-6 pathway, the higher the inhibition rate of C-reactive protein(CRP) at downstream of IL-6 by the combination of chlorogenic acid and luteolin.	Chlorogenic Acid	178-194	interleukin 6	Homo sapiens	342-346	
30547263-6	2019	However, in the absence of LPS, IL-6 secretion was significantly increased in response to 2 microM of either cyanidin or chlorogenic acid (both p < 0.0001), as well as the combination treatment (p < 0.01).	Chlorogenic Acid	121-137	interleukin 6	Homo sapiens	32-36