PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20637839-0	2010	Chlorogenic acid suppresses pulmonary eosinophilia, IgE production, and Th2-type cytokine production in an ovalbumin-induced allergic asthma: activation of STAT-6 and JNK is inhibited by chlorogenic acid.	Chlorogenic Acid	0-16	mitogen-activated protein kinase 8	Mus musculus	167-170	
20637839-0	2010	Chlorogenic acid suppresses pulmonary eosinophilia, IgE production, and Th2-type cytokine production in an ovalbumin-induced allergic asthma: activation of STAT-6 and JNK is inhibited by chlorogenic acid.	Chlorogenic Acid	187-203	mitogen-activated protein kinase 8	Mus musculus	167-170	
19393773-0	2009	Chlorogenic acid inhibits lipopolysaccharide-induced cyclooxygenase-2 expression in RAW264.7 cells through suppressing NF-kappaB and JNK/AP-1 activation.	Chlorogenic Acid	0-16	mitogen-activated protein kinase 8	Mus musculus	133-136	
31139644-6	2019	Chlorogenic acid reduces DSS-induced colonic mucosal damage, inhibits DSS-induced inflammation, oxidative stress, and apoptosis in colon, and reduces ERK1/2, p -ERK, p38, p-p38, JNK, and p-JNK protein expression.	Chlorogenic Acid	0-16	mitogen-activated protein kinase 8	Mus musculus	178-181	
31139644-0	2019	Chlorogenic Acid Attenuates Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice through MAPK/ERK/JNK Pathway.	Chlorogenic Acid	0-16	mitogen-activated protein kinase 8	Mus musculus	103-106	
31139644-4	2019	The relationship between chlorogenic acid and MAPK/ERK/JNK signaling pathway was explored by adding ERK inhibitor.	Chlorogenic Acid	25-41	mitogen-activated protein kinase 8	Mus musculus	55-58	
31139644-6	2019	Chlorogenic acid reduces DSS-induced colonic mucosal damage, inhibits DSS-induced inflammation, oxidative stress, and apoptosis in colon, and reduces ERK1/2, p -ERK, p38, p-p38, JNK, and p-JNK protein expression.	Chlorogenic Acid	0-16	mitogen-activated protein kinase 8	Mus musculus	189-192	
31139644-8	2019	Conclusion: Chlorogenic acid can alleviate DSS-induced ulcerative colitis in mice, which can significantly reduce tissue inflammation and apoptosis, and its mechanism is related to the MAPK/ERK/JNK signaling pathway.	Chlorogenic Acid	12-28	mitogen-activated protein kinase 8	Mus musculus	194-197	
30165128-4	2018	Furthermore, ChA administration resulted in a suppression of phosphorylated extracellular signal-regulated kinases 1 and 2 (ERK1/2), c-Jun N-terminal kinases 1 and 2 (JNK1/2), Akt and signal transducer and activator of transcription 3 (STAT3) with concomitant upregulation of phosphatase and tensin homolog (PTEN) expression.	Chlorogenic Acid	13-16	mitogen-activated protein kinase 8	Mus musculus	133-165	
30165128-4	2018	Furthermore, ChA administration resulted in a suppression of phosphorylated extracellular signal-regulated kinases 1 and 2 (ERK1/2), c-Jun N-terminal kinases 1 and 2 (JNK1/2), Akt and signal transducer and activator of transcription 3 (STAT3) with concomitant upregulation of phosphatase and tensin homolog (PTEN) expression.	Chlorogenic Acid	13-16	mitogen-activated protein kinase 8	Mus musculus	167-173	
23168580-4	2013	The mechanisms of action of chlorogenic acid included attenuation of the increase in toll-like receptor (TLR)-4 expression and suppression of sepsis-induced signaling pathways, such as c-Jun NH2-terminal kinase (JNK), p38 mitogen-activated protein kinase (MAPK) and nuclear factor (NF)-kappaB, which are critical for cytokine release.	Chlorogenic Acid	28-44	mitogen-activated protein kinase 8	Mus musculus	185-210	
23168580-4	2013	The mechanisms of action of chlorogenic acid included attenuation of the increase in toll-like receptor (TLR)-4 expression and suppression of sepsis-induced signaling pathways, such as c-Jun NH2-terminal kinase (JNK), p38 mitogen-activated protein kinase (MAPK) and nuclear factor (NF)-kappaB, which are critical for cytokine release.	Chlorogenic Acid	28-44	mitogen-activated protein kinase 8	Mus musculus	212-215