PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15944151-9	2005	Further studies indicated that chlorogenic acid could stimulate the nuclear translocation of Nrf2 (NF-E2-related factor) as well as subsequent induction of GSTA1 antioxidant response element (ARE)-mediated GST activity.	Chlorogenic Acid	31-47	NFE2 like bZIP transcription factor 2	Homo sapiens	93-97	
35313270-0	2022	Chlorogenic acid attenuates inflammation in LPS-induced Human gingival fibroblasts via CysLT1R/Nrf2/NLRP3 signaling.	Chlorogenic Acid	0-16	NFE2 like bZIP transcription factor 2	Homo sapiens	95-99	
32981407-2	2020	OBJECTIVE: We investigated whether 5-CQA had a cytoprotective effect through the NF-E2-related factor 2 (Nrf2)-antioxidant response element (ARE) signalling pathway.	Chlorogenic Acid	35-40	NFE2 like bZIP transcription factor 2	Homo sapiens	81-103	
32981407-2	2020	OBJECTIVE: We investigated whether 5-CQA had a cytoprotective effect through the NF-E2-related factor 2 (Nrf2)-antioxidant response element (ARE) signalling pathway.	Chlorogenic Acid	35-40	NFE2 like bZIP transcription factor 2	Homo sapiens	105-109	
32981407-3	2020	MATERIALS AND METHODS: Nrf2 activation in response to 5-CQA treatment at the concentration of 10-100 muM is evaluated by Western blotting of Nrf2 and ARE reporter gene assay as well as its target gene expression in HepG2 cells.	Chlorogenic Acid	54-59	NFE2 like bZIP transcription factor 2	Homo sapiens	23-27	
32981407-3	2020	MATERIALS AND METHODS: Nrf2 activation in response to 5-CQA treatment at the concentration of 10-100 muM is evaluated by Western blotting of Nrf2 and ARE reporter gene assay as well as its target gene expression in HepG2 cells.	Chlorogenic Acid	54-59	NFE2 like bZIP transcription factor 2	Homo sapiens	141-145	
32981407-5	2020	The specific role of 5-CQA on Nrf2 activation was examined using Nrf2 knockout cells or Nrf2 specific inhibitor, ML-385.	Chlorogenic Acid	21-26	NFE2 like bZIP transcription factor 2	Homo sapiens	30-34	
32981407-7	2020	Nrf2 deficiency or inhibition completely antagonized ability of 5-CQA to induce HO-1 and GCL expression.	Chlorogenic Acid	64-69	NFE2 like bZIP transcription factor 2	Homo sapiens	0-4	
32981407-10	2020	DISCUSSION AND CONCLUSIONS: Taken together, our results demonstrate that as a novel Nrf2 activator, 5-CQA, may be a promising candidate against oxidative stress-mediated liver injury.	Chlorogenic Acid	100-105	NFE2 like bZIP transcription factor 2	Homo sapiens	84-88	
30895499-0	2019	Chlorogenic acid isomers directly interact with Keap 1-Nrf2 signaling in Caco-2 cells.	Chlorogenic Acid	0-16	NFE2 like bZIP transcription factor 2	Homo sapiens	55-59	
30259744-0	2018	Amelioration of Oxidative Stress in Caco-2 Cells Treated with Pro-inflammatory Proteins by Chlorogenic Acid Isomers via Activation of the Nrf2-Keap1-ARE-Signaling Pathway.	Chlorogenic Acid	91-107	NFE2 like bZIP transcription factor 2	Homo sapiens	138-142	
21448860-0	2011	Coffees rich in chlorogenic acid or N-methylpyridinium induce chemopreventive phase II-enzymes via the Nrf2/ARE pathway in vitro and in vivo.	Chlorogenic Acid	16-32	NFE2 like bZIP transcription factor 2	Homo sapiens	103-107