PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1586993-0	1992	DNA sequence analysis of 1-nitrosopyrene-induced mutations in the hprt gene of Chinese hamster ovary cells.	1-nitrosopyrene	25-40	hypoxanthine-guanine phosphoribosyltransferase	Cricetulus griseus	66-70	
1586993-1	1992	DNA sequence was determined in 21 mutants induced at the hprt locus of Chinese hamster ovary (CHO) cells by 1-nitrosopyrene, a metabolite of the tumorigenic environmental pollutant 1-nitropyrene.	1-nitrosopyrene	108-123	hypoxanthine-guanine phosphoribosyltransferase	Cricetulus griseus	57-61	
1586993-8	1992	The results indicate a specificity for the induction of mutations in the hprt gene of CHO cells by 1-nitrosopyrene with respect to both the types of mutations produced and their location in the hprt gene.	1-nitrosopyrene	99-114	hypoxanthine-guanine phosphoribosyltransferase	Cricetulus griseus	73-77	
1586993-8	1992	The results indicate a specificity for the induction of mutations in the hprt gene of CHO cells by 1-nitrosopyrene with respect to both the types of mutations produced and their location in the hprt gene.	1-nitrosopyrene	99-114	hypoxanthine-guanine phosphoribosyltransferase	Cricetulus griseus	194-198	
1541256-1	1992	1-Nitrosopyrene, a metabolite of the tumorigenic environmental pollutant 1-nitropyrene, is a potent mutagen at the hprt locus in Chinese hamster ovary (CHO) cells.	1-nitrosopyrene	0-15	hypoxanthine-guanine phosphoribosyltransferase	Cricetulus griseus	115-119	
1541256-7	1992	Using polymerase chain reaction amplification of cDNA synthesized from RNA, the hprt protein-coding region could be amplified from 23 of the 1-nitrosopyrene-induced mutants and 11 of the control mutants.	1-nitrosopyrene	141-156	hypoxanthine-guanine phosphoribosyltransferase	Cricetulus griseus	80-84	
1541256-10	1992	A large number of both control and 1-nitrosopyrene-induced mutants exhibited a marked reduction in hprt mRNA concentration or possessed truncated mRNA hprt protein coding sequence.	1-nitrosopyrene	35-50	hypoxanthine-guanine phosphoribosyltransferase	Cricetulus griseus	99-103	
1541256-10	1992	A large number of both control and 1-nitrosopyrene-induced mutants exhibited a marked reduction in hprt mRNA concentration or possessed truncated mRNA hprt protein coding sequence.	1-nitrosopyrene	35-50	hypoxanthine-guanine phosphoribosyltransferase	Cricetulus griseus	151-155