PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25344147-1	2015	PURPOSE: We tested whether positron emission tomography (PET) with the caspase-3-targeted isatin analog [(18)F]WC-4-116 could image caspase-3 activation in response to an apoptosis-inducing anticancer therapy.	Isatin	90-96	caspase 3	Mus musculus	71-80	
25344147-1	2015	PURPOSE: We tested whether positron emission tomography (PET) with the caspase-3-targeted isatin analog [(18)F]WC-4-116 could image caspase-3 activation in response to an apoptosis-inducing anticancer therapy.	Isatin	90-96	caspase 3	Mus musculus	132-141	
22033021-0	2012	Radiolabeled isatin binding to caspase-3 activation induced by anti-Fas antibody.	Isatin	13-19	caspase 3	Mus musculus	31-40	
22033021-2	2012	We evaluated the ability of radiolabeled isatins to quantify caspase-3 activity induced by the activation of the extrinsic apoptotic pathway by the anti-Fas antibody in mice.	Isatin	41-48	caspase 3	Mus musculus	61-70	
22033021-9	2012	The isatin [(18)F]WC-II-89 was retained at statistically significantly higher levels in the organs after anti-Fas antibody treatment while [(99m)Tc]mebrofenin activity cleared, suggesting specific binding to activated caspase-3, but the magnitude of increased binding was still relatively low.	Isatin	4-10	caspase 3	Mus musculus	218-227	
22033021-11	2012	CONCLUSIONS: The radiolabeled isatins appear to bind specifically to caspase-3 in vivo, but their sensitivity is limited.	Isatin	30-37	caspase 3	Mus musculus	69-78