PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28414290-6 2017 The SPR-based experiments have shown that a high concentration of isatin (270 mM) increases Kd values for complexes CYB5A/CYP3A5 and CYB5A/CYP3A4 (twofold and threefold, respectively), but has no influence on complex formation between CYB5A and other CYP (including indol-metabolizing CYP2C19 and CYP2E1). Isatin 66-72 cytochrome P450 family 3 subfamily A member 5 Homo sapiens 122-128 28414290-8 2017 Molecular docking manipulations have shown that isatin can influence interaction of CYP3A5 or CYP3A4 with CYB5A acting at the contact region of CYB5A/CYP. Isatin 48-54 cytochrome P450 family 3 subfamily A member 5 Homo sapiens 84-90