PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29340222-6	2017	Importantly, the TBXAS1 CYP2E1 complex formation increases fivefold in the presence of isatin (indole-2,3-dione, a low-molecular nonpeptide endogenous bioregulator, a product of CYP2E1).	Isatin	87-93	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	24-30	
29340222-6	2017	Importantly, the TBXAS1 CYP2E1 complex formation increases fivefold in the presence of isatin (indole-2,3-dione, a low-molecular nonpeptide endogenous bioregulator, a product of CYP2E1).	Isatin	87-93	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	178-184	
29340222-6	2017	Importantly, the TBXAS1 CYP2E1 complex formation increases fivefold in the presence of isatin (indole-2,3-dione, a low-molecular nonpeptide endogenous bioregulator, a product of CYP2E1).	Isatin	95-111	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	24-30	
29340222-6	2017	Importantly, the TBXAS1 CYP2E1 complex formation increases fivefold in the presence of isatin (indole-2,3-dione, a low-molecular nonpeptide endogenous bioregulator, a product of CYP2E1).	Isatin	95-111	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	178-184	
28414290-2	2017	Since some CYP catalyze indol oxidation to isatin, we have hypothesized that isatin can regulate protein-protein interactions (PPI) between components of the CYP system thus representing a (negative?)	Isatin	43-49	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	158-161	
28414290-2	2017	Since some CYP catalyze indol oxidation to isatin, we have hypothesized that isatin can regulate protein-protein interactions (PPI) between components of the CYP system thus representing a (negative?)	Isatin	77-83	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	11-14	
28414290-2	2017	Since some CYP catalyze indol oxidation to isatin, we have hypothesized that isatin can regulate protein-protein interactions (PPI) between components of the CYP system thus representing a (negative?)	Isatin	77-83	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	158-161	
28414290-4	2017	The aim of this study was to investigate a possible effect of isatin on interaction of human CYP with cytochrome b5 (CYB5A).	Isatin	62-68	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	93-96	
28414290-6	2017	The SPR-based experiments have shown that a high concentration of isatin (270 mM) increases Kd values for complexes CYB5A/CYP3A5 and CYB5A/CYP3A4 (twofold and threefold, respectively), but has no influence on complex formation between CYB5A and other CYP (including indol-metabolizing CYP2C19 and CYP2E1).	Isatin	66-72	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	122-125	
28414290-6	2017	The SPR-based experiments have shown that a high concentration of isatin (270 mM) increases Kd values for complexes CYB5A/CYP3A5 and CYB5A/CYP3A4 (twofold and threefold, respectively), but has no influence on complex formation between CYB5A and other CYP (including indol-metabolizing CYP2C19 and CYP2E1).	Isatin	66-72	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	297-303	
28414290-8	2017	Molecular docking manipulations have shown that isatin can influence interaction of CYP3A5 or CYP3A4 with CYB5A acting at the contact region of CYB5A/CYP.	Isatin	48-54	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	84-87