PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17869226-9 2007 Moreover, DHTS activated caspase-9, caspase-3, and caspase-7 and caused cell apoptosis. dhts 10-14 caspase 3 Homo sapiens 36-45 26478521-8 2017 In addition, DHTI induced apoptosis of 143B cells through caspase pathways to activate caspase-3, caspase-8, caspase-9, Bax, and PARP cleavage but reduce the expression of Bcl-2. dhts 13-17 caspase 3 Homo sapiens 87-96 26287183-3 2015 We found that treatment with 1.5 mug/mL DHTS increased proapoptotic Bax and Bad protein expressions and activated caspases-3, -8, and -9, thus leading to poly ADP ribose polymerase (PARP) cleavage and resulting in cell apoptosis. dhts 40-44 caspase 3 Homo sapiens 114-136 26287183-5 2015 The anti-Fas blocking antibody reversed the DHTS-induced cell death, and the JNK-specific inhibitor, SP600125, inhibited DHTS-induced caspase-3, -8, -9, and PARP cleavage. dhts 121-125 caspase 3 Homo sapiens 134-151 17869226-10 2007 The fact that DHTS-induced apoptosis could be blocked by pretreating cells with pan-caspase inhibitor confirmed that it is mediated through activation of the caspase-3-dependent pathway. dhts 14-18 caspase 3 Homo sapiens 158-167