PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15110098-6	2004	The administration of high doses of TB resulted in the induction of 7-ethoxyresorufin O-deethylase and 7-pentoxyresorufin O-depentylase activities, CYP1A1, CYP1A2, CYP2B1 and CYP2B1/2 mRNA levels and CYP1A2 and CYP2B1/2 apoprotein levels.	Thiabendazole	36-38	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	148-154	
14987951-0	2004	The role of protein tyrosine kinases in CYP1A1 induction by omeprazole and thiabendazole in rat hepatocytes.	Thiabendazole	75-88	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	40-46	
14987951-1	2004	Benzimidazoles compounds like omeprazole (OME) and thiabendazole (TBZ) mediate CYP1A1 induction differently from classical aryl hydrocarbon receptor (AhR) ligands, 3-methylcholanthrene (3-MC) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).	Thiabendazole	51-64	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	79-85	
14987951-1	2004	Benzimidazoles compounds like omeprazole (OME) and thiabendazole (TBZ) mediate CYP1A1 induction differently from classical aryl hydrocarbon receptor (AhR) ligands, 3-methylcholanthrene (3-MC) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).	Thiabendazole	66-69	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	79-85	
14987951-2	2004	To clarify the involvement of an intracellular signal pathway in CYP1A1 induction by OME and TBZ, the TBZ, OME and 3-MC signal-transducing pathways were compared by using specific protein tyrosine kinase inhibitors in primary culture of rat hepatocytes.	Thiabendazole	93-96	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	65-71	
14987951-3	2004	The effect of OME and TBZ (75-250 microM) on cytochrome P450 1A1 (CYP1A1) expression was therefore studied in primary cultures of rat hepatocytes after 24 h, 48 h and 72 h of exposure.	Thiabendazole	22-25	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	45-64	
14987951-3	2004	The effect of OME and TBZ (75-250 microM) on cytochrome P450 1A1 (CYP1A1) expression was therefore studied in primary cultures of rat hepatocytes after 24 h, 48 h and 72 h of exposure.	Thiabendazole	22-25	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	66-72	
10103034-2	1999	Omeprazole, thiabendazole, carbendazim, 2-mercaptobenzimidazole and 2-mercapto-5-methoxybenzimidazole caused a dose-dependent increase in CYP1A1 protein levels that reached maximum effect at 250 microm, as measured by Western blot.	Thiabendazole	12-25	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	138-144	
10103034-5	1999	Northern blot analysis confirmed an extensive increase of CYP1A1 mRNA induced by omeprazole and 2-mercapto-5-methoxybenzimidazole which was 32% and 49% of maximal induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) respectively, whereas thiabendazole and carbendazim showed approximately 15% increase as compared to TCDD.	Thiabendazole	241-254	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	58-64