PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23959266-6 2013 The observed synergy between gefitinib and 5"-DFUR has inspired the design of single molecules capable of acting as prodrugs of both an EGFR inhibitor and 5-FU. 5"-dfur 43-50 epidermal growth factor receptor Homo sapiens 136-140 23959266-12 2013 Our results in toto, suggest that capecitabine-based EGFR targeting combi-molecules of the same type than ZRX1, have the potential to induce stronger growth inhibitory potency than capecitabine, 5"-DFUR or single EGFR inhibitors and equivalent potency when compared with combinations of EGFR inhibitors + 5"-DFUR. 5"-dfur 195-202 epidermal growth factor receptor Homo sapiens 53-57 23959266-12 2013 Our results in toto, suggest that capecitabine-based EGFR targeting combi-molecules of the same type than ZRX1, have the potential to induce stronger growth inhibitory potency than capecitabine, 5"-DFUR or single EGFR inhibitors and equivalent potency when compared with combinations of EGFR inhibitors + 5"-DFUR. 5"-dfur 305-312 epidermal growth factor receptor Homo sapiens 53-57 21915635-0 2012 Inhibition of EGFR phosphorylation in a panel of human breast cancer cells correlates with synergistic interactions between gefitinib and 5"-DFUR, the bioactive metabolite of Xeloda. 5"-dfur 138-145 epidermal growth factor receptor Homo sapiens 14-18 21915635-4 2012 Prior work in head and neck cancer showed that cell treatment with an inhibitor of the epidermal growth receptor (EGFR) gefitinib led to an increase in TP expression and sensitized them to 5"-DFUR. 5"-dfur 189-196 epidermal growth factor receptor Homo sapiens 114-118