PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30609271-9	2019	In addition, melatonin was demonstrated to preserve the extracellular matrix (ECM) content of Collagen II, Aggrecan and Sox-9, while inhibiting the expression of matrix degeneration enzymes, including MMP-13 and ADAMTS-5.	Melatonin	13-22	ADAM metallopeptidase with thrombospondin type 1 motif 5	Homo sapiens	212-220	
31915516-4	2019	In an in vitro OA environment induced by interleukin-1 beta (IL-1beta), melatonin treatment improved cell proliferation of human chondrocytes, promoted the expression of cartilage ECM proteins (e.g., type II collagen and aggrecan), and inhibited the levels of IL-1beta-induced proteinases, such as matrix metalloproteinase 9 (MMP9), MMP13, ADAMTS4 (a disintegrin and metalloproteinase with thrombospondin motifs 4), and ADAMTS5.	Melatonin	72-81	ADAM metallopeptidase with thrombospondin type 1 motif 5	Homo sapiens	420-427