PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25988948-7	2015	Melatonin significantly increased hippocampal synaptic density and the number of excitatory synapses, decreased the number of inhibitory synapses, and upregulated pre- and postsynaptic proteins (synapsin I and PSD-95, respectively).	Melatonin	0-9	discs large MAGUK scaffold protein 4	Rattus norvegicus	210-216	
29149481-7	2018	Melatonin attenuated the reduction in the expression of hippocampal synaptophysin, PSD-95, alpha-synuclein, and N-methyl-D-aspartate (NMDA) receptor protein and mRNA caused by AMPH.	Melatonin	0-9	discs large MAGUK scaffold protein 4	Rattus norvegicus	83-89	
24350898-0	2014	Melatonin improves neuroplasticity by upregulating the growth-associated protein-43 (GAP-43) and NMDAR postsynaptic density-95 (PSD-95) proteins in cultured neurons exposed to glutamate excitotoxicity and in rats subjected to transient focal cerebral ischemia even during a long-term recovery period.	Melatonin	0-9	discs large MAGUK scaffold protein 4	Rattus norvegicus	128-134	
24350898-2	2014	Here, we evaluated whether melatonin would modulate the PSD-95, GAP-43, and MMP-9 proteins in cultured neurons exposed to glutamate excitotoxicity and in rats subjected to experimental stroke.	Melatonin	27-36	discs large MAGUK scaffold protein 4	Rattus norvegicus	56-62	
24350898-6	2014	In cultured neurons exposed to glutamate excitotoxicity, melatonin significantly upregulated the GAP-43 and PSD-95 expressions and improved dendritic aborizations (P<0.05, respectively).	Melatonin	57-66	discs large MAGUK scaffold protein 4	Rattus norvegicus	108-114	
24350898-7	2014	Relative to controls, melatonin-treated stroke animals caused a significant improvement in GAP-43 and PSD-95 expressions as well as the MMP-9 activity in the ischemic brain (P<0.05).	Melatonin	22-31	discs large MAGUK scaffold protein 4	Rattus norvegicus	102-108	
24350898-9	2014	Together, melatonin upregulates GAP-43, PSD-95, and MMP-9 proteins, which likely accounts for its actions to improve neuroplasticity in cultured neurons exposed to glutamate excitotoxicity and to enhance long-term neuroprotection, neuroplasticity, and brain remodeling in stroke rats.	Melatonin	10-19	discs large MAGUK scaffold protein 4	Rattus norvegicus	40-46