PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35179606-5 2022 In vitro potency of IOP toward DIOs was evaluated using previously developed in vitro screening assays, which showed concentration-dependent inhibition of human DIO1 (IC50: 97 microM) and DIO2 (IC50: 231 microM) but did not inhibit human or X. laevis DIO3 under the assay conditions. dios 31-35 iodothyronine deiodinase 2 Homo sapiens 188-192